Evidence map›Paper›PMID 31747489›Full record

ArticleThe Journal of clinical psychiatry2019

Prescription Opioid Misuse in US Older Adults: Associated Comorbidities and Reduced Quality of Life in the National Epidemiologic Survey of Alcohol and Related Conditions-III.

Ty S Schepis, Sean Esteban McCabe

Abstract read
In one paragraph

Article in The Journal of clinical psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Prescription Drug Misuse: Taking a Lifespan Perspective.Substance abuse : research and treatment · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ty S SchepisDepartment of Psychology, Texas State University, 601 University Dr, San Marcos, TX 78666. schepis@txstate.edu.
Sean Esteban McCabeCenter for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, Michigan, USA.

Funding

Trajectories of Prescription Nonmedical Drug MisuseR01DA031160 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEAN ESTEBAN MCCABE · 2011 to 2026
$3.7M
Discrimination, Stress and Substance Use Disorder among Sexual Minority Adults: A Secondary Analysis of NESARC-IIIR01DA043696 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOYD, CAROL J · 2017 to 2019
$1.1M
Sexual Orientation, Discrimination, and Health Disparities in DSM-5 Alcohol Use DisordersR01AA025684 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCABE, SEAN ESTEBAN · 2018 to 2020
$855k
Health, Stress, and Tobacco Use Disparities among Sexual Minority PopulationsR01CA212517 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCABE, SEAN ESTEBAN · 2017 to 2019
$721k
Longitudinal Changes in Recovery from Drug Use Disorders: A National StudyR01DA036541 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCABE, SEAN ESTEBAN · 2015 to 2017
$647k
Nonmedical prescription drug misuse among US older adults: subtypes,motives, and diversion sourcesR01DA042146 · NIDA · TEXAS STATE UNIVERSITY · PI SCHEPIS, TY STEPHEN · 2017 to 2021
$548k
NCI NIH HHS R01 CA212517NIAAA NIH HHS R01 AA025684NIDA NIH HHS R01 DA031160NIDA NIH HHS R01 DA036541NIDA NIH HHS R01 DA042146NIDA NIH HHS R01 DA043696
6 · The paper itself

Abstract

objectivePrescription opioid misuse (POM) prevalence in US older adults (50 years and older) has increased, and preliminary evidence associates POM with poor outcomes. Despite this, little is known about the health-related quality of life, mental and physical health, and substance use profiles of older adults with current and/or past POM. The aim of this study was to evaluate differences in these variables by POM history in US older adults.

methodsData were from the 2012-2013 National Epidemiologic Survey of Alcohol and Related Conditions-III, using adults 50 years and older (n = 14,667). Respondents were grouped into mutually exclusive categories: no lifetime POM, prior-to-past-year POM, past-year POM, and persistent POM (ie, prior-to-past-year and past-year POM). Groups were compared using design-based linear regression on health-related quality of life and logistic regression on mental health, physical health, and substance use variables, controlling for sociodemographics.

resultsOlder adults with persistent POM had the greatest impairment, including lower mental and physical health-related quality of life and high rates of past-year major depression (17.6%), emergency department use (42.7%), and any substance use disorder (37.4%). Older adults with past-year POM had high rates of physical health diagnoses and health care utilization (eg, 45.6% past-year overnight hospitalization), while those with prior-to-past-year POM had significant current psychopathology (eg, 13.7% with past-year major depression).

conclusionsOlder adults with persistent POM likely need multidisciplinary care for their significant physical and mental health and substance use conditions. Given the elevated psychopathology in those with persistent POM, psychiatrists are well placed to identify those with long-term POM.

Indexed as

AgedAlcoholismAnxiety DisordersComorbidityFemaleHumansMaleMiddle AgedMood DisordersOpioid-Related DisordersPrevalenceQuality of LifeStress Disorders, Post-TraumaticSubstance-Related DisordersUnited States

Identifiers

PMID31747489
PMCPMC6935372

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.