Evidence map›Paper›PMID 31747396›Full record

ArticlePloS one2019

Why men with a low-risk prostate cancer select and stay on active surveillance: A qualitative study.

Aaron T Seaman, Kathryn L Taylor, Kimberly Davis, Kenneth G Nepple, John H Lynch, Anthony D Oberle, Ingrid J Hall, Robert J Volk, Heather Schacht Reisinger, Richard M Hoffman

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Comparative analysis of treatment decision-making in patients with localized prostate and cervical cancer: what influences receiving surgery or radiotherapy?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  5. Article
  6. Article
  7. Psychological aspects of active surveillance.World journal of urology · 2022
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aaron T SeamanDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America.
Kathryn L TaylorCancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, United States of America.
Kimberly DavisCancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, United States of America.
Kenneth G NeppleDepartment of Urology, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America.
John H LynchDepartment of Urology, Georgetown University, Washington, DC, United States of America.
Anthony D OberleDepartment of Urology, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America.
Ingrid J HallEpidemiology and Applied Research Branch, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, United States of America.
Robert J VolkDepartment of Health Services Research, Division of Cancer Prevention and Population Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Heather Schacht ReisingerDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America.ORCID 0000-0002-5348-063X
Richard M HoffmanDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, United States of America.ORCID 0000-0002-4714-7726

Funding

Center for Health Promotion and Disease PreventionU48DP005017 · DP · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AMMERMAN, ALICE S, WHEELER, STEPHANIE BROOKE · 2014 to 2018
$10.9M
ACL HHS U48DP005017NCCDPHP CDC HHS U48 DP005017
6 · The paper itself

Abstract

objectiveActive surveillance (AS) is an increasingly utilized strategy for monitoring men with low-risk prostate cancer (PCa) that allows them to defer active treatment (AT) in the absence of cancer progression. Studies have explored reasons for selecting AS and for then switching to AT, but less is known about men's experiences being on AS. We interviewed men to determine the clinical and psychological factors associated with selecting and adhering to AS protocols.

methodsWe conducted semi-structured interviews with men with a low-risk PCa at two academic medical centers. Subjects had either been on AS for ≥ 1 year or had opted for AT after a period of AS. We used an iterative, content-driven approach to analyze the interviews and to identify themes.

resultsWe enrolled 21 subjects, mean age 70.4 years, 3 racial/ethnic minorities, and 16 still on AS. Men recognized the favorable prognosis of their cancer (some had sought second opinions when initially offered AT), valued avoiding treatment complications, were reassured that close monitoring would identify progression early enough to be successfully treated, and trusted their urologists. Although men reported feeling anxious around the time of surveillance testing, those who switched to AT did so based only on evidence of cancer progression.

conclusionsOur selected sample was comfortable being on AS because they understood and valued the rationale for this approach. However, this highlights the importance of ensuring that men newly diagnosed with a low-risk PCa are provided sufficient information about prognosis and treatment options to make informed decisions.

Indexed as

Chronic Disease IndicatorsHealth Knowledge, Attitudes, PracticeAged, 80 and overHumansMaleMiddle AgedPatientsProstatic Neoplasms

Identifiers

PMID31747396
PMCPMC6867634

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.