Observational studyActa paediatrica (Oslo, Norway : 1992)2020
Unpasteurised maternal breast milk is positively associated with growth outcomes in extremely preterm infants.
Observational study in Acta paediatrica (Oslo, Norway : 1992), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Association between viral infection and bronchopulmonary dysplasia in preterm infants: a systematic review and meta-analysis.European journal of pediatrics · 2024Pooled it
- Modification of serum fatty acids in preterm infants by parenteral lipids and enteral docosahexaenoic acid/arachidonic acid: A secondary analysis of the Mega Donna Mega trial.Clinical nutrition (Edinburgh, Scotland) · 2023Trial
- Impact of Access to Pasteurised Donor Human Milk on Rates of Necrotising Enterocolitis in Neonatal Units in Australia: A Cohort Study.Journal of paediatrics and child health · 2026Article
- Impact of fortifiers on donor milk nutrient composition: An experimental study.JPEN. Journal of parenteral and enteral nutrition · 2026Article
- Article
- Factors associated with the increased incidence of necrotising enterocolitis in extremely preterm infants in Sweden between two population-based national cohorts (2004-2007 vs 2014-2016).Archives of disease in childhood. Fetal and neonatal edition · 2023Article
- Longitudinal Serum Metabolomics in Extremely Premature Infants: Relationships With Gestational Age, Nutrition, and Morbidities.Frontiers in neuroscience · 2022Article
- Serum choline in extremely preterm infants declines with increasing parenteral nutrition.European journal of nutrition · 2021Article
- Influence of Nutrition and Maternal Bonding on Postnatal Lung Development in the Newborn Pig.Frontiers in immunology · 2021Article
- Unpasteurised maternal breast milk is positively associated with growth outcomes in extremely preterm infants.Acta paediatrica (Oslo, Norway : 1992) · 2020Observational
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimExtrauterine growth restriction is common among extremely preterm infants. We explored whether intake of unpasteurised maternal milk (MM) and pasteurised donor milk (DM) was associated with longitudinal growth outcomes and neonatal morbidities in extremely preterm infants.
methodsObservational study of 90 preterm infants born between 2013 and 2015 in Gothenburg, Sweden. Data were prospectively collected on nutritional and breast milk intakes during the first 28 days.
resultsNinety infants (39 girls and 51 boys) with a median gestational age of 25.3 (22.7-27.9) weeks were evaluated. MM intake (mL/kg/d) correlated positively with almost all z-scores for weight, length and head circumference at 28 postnatal days and at postmenstrual age (PMA) 32 and 36 weeks. After multivariable adjustment, MM intake and weight z-score at 28 postnatal days and at PMA 32 and 36 weeks remained significantly associated. Infants consuming ≥80% MM had more favourable weight z-scores at PMA 32 and 36 weeks. Intake of DM did not correlate with any growth outcomes. Infants without retinopathy of prematurity had a significantly higher intake of MM (mL/kg/d).
conclusionUnpasteurised MM was positively associated with longitudinal growth outcomes. Motivating mothers to provide their infants with their own milk after preterm birth should be emphasised.
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