Evidence map›Paper›PMID 31746943›Full record

ReviewCardiovascular journal of Africa

Renal denervation: dark past, bright future?

Marshall Heradien, Felix Mahfoud, Doug Hettrick, Paul Brink

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cardiovascular journal of Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Renal denervation: bleak past, brighter future.Cardiovascular journal of Africa
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Marshall HeradienDepartment of Internal Medicine, Stellenbosch University, Cape Town, South Africa. Email: hartspesialis@gmail.com.
Felix MahfoudKlinik für Innere Medizin III, Saarland University Hospital, Homburg, Saarland, Germany.
Doug HettrickCoronary and Renal Denervation, Medtronic, Santa Rosa, CA 95403, United States of America.
Paul BrinkDepartment of Internal Medicine, Stellenbosch University, Cape Town, South Africa.
Saarland University · DEStellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this review is to update the reader on the relevance of autonomic nervous system imbalance in clinical cardiology. Increased sympathetic tone associates with the metabolic syndrome, hypertension and cardiac arrhythmias. With the kidneys playing a pivotal role in increased peripheral resistance, sodium and water retention and other mechanisms, renal denervation (RD) may theoretically restore autonomic imbalance and improve cardiovascular outcomes. Landmark RD trials and novel uses for RD in cardiac arrhythmia management are discussed.

Indexed as

AnimalsAtrial FibrillationAutonomic DenervationAutonomic Nervous SystemDiffusion of InnovationEvidence-Based MedicineForecastingHumansHypertensionKidneyRandomized Controlled Trials as TopicRisk FactorsTreatment Outcomeatrial fibrillationautonomic imbalancehypertensionhypertensive heart diseaserenal denervation

Identifiers

PMID31746943
PMCPMC8802378
OpenAlexW2984922169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.