Trial reportEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2021
Radial artery dilatation to improve access and lower complications during coronary angiography: the RADIAL trial.
Trial report in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05364463 (Randomized Clinical Trial on the Effect of Reactive Hyperemia and Ultrasound-guided Puncture on the Success Rate of Radial Artery Cannulation in Patients Undergoing Cardiac Catheterization), which is not on this map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Clinical Trial on the Effect of Reactive Hyperemia and Ultrasound-guided Puncture on the Success Rate of Radial Artery Cannulation in Patients Undergoing Cardiac Catheterization
Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Radial Access Strategies: Focus on Coronary Function Testing for Angina With Nonobstructive Coronary Arteries.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Review
- Radial artery characteristics before and after intra-arterial administration of nitroglycerin and verapamil: an optical coherence tomography study.Frontiers in medicine · 2026Article
- Evaluation of Pulse Wave Analysis for Detecting Arterial Tone Changes During Transradial Access Coronary Angiography.Cureus · 2025Article
- A predictive model discloses independent risk factors for vascular complications in elderly cerebrovascular accident patients after trans-radial access cerebral angiography.American journal of translational research · 2025Article
- Radial Artery Spasm-A Review on Incidence, Prevention and Treatment.Diagnostics (Basel, Switzerland) · 2024Review
- Reduced Radial Artery Occlusion in Transradial Cerebral Angiography: Key Predictive Factors and Preventive Measures from a Single-Center Study of 543 Patients.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Flow-mediated dilatation facilitates transradial coronary angiography: a comparative study.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024Article
- Development and validation of a nomogram for predicting difficult radial artery cannulation in adult surgical patients.Heliyon · 2024Article
- Investigating optimal compression approach following radial artery puncture: a retrospective study.American journal of translational research · 2024Article
- The optimal puncture time point of prolonged occlusion flow-mediated dilatation in radial artery catheterization: a prospective observational study.Scientific reports · 2023Observational
- Preventing and Managing Radial Artery Occlusion following Transradial Procedures: Strategies and Considerations.Journal of cardiovascular development and disease · 2023Review
- Pumping up best practices in radial artery access: prolonged occlusion flow-mediated dilation improves radial artery access success.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021Article
- Vascular Complications of Transradial Access for Cardiac Catheterization.US cardiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe aim of this study was to explore the use of prolonged occlusion flow-mediated dilatation (PO-FMD) to dilate the radial artery prior to cannulation to increase cannulation success, reduce puncture attempts and reduce access-site complications in transradial coronary angiography. METHODS AND
resultsA total of 1,156 patients undergoing transradial coronary angiography were randomised into PO-FMD and sham PO-FMD groups. PO-FMD was achieved by a 10-minute inflation of a blood pressure cuff on the arm to above systolic pressure, followed by deflation with resultant radial artery dilation. In the sham PO-FMD group the cuff was not inflated. Operators were blinded to the intervention. Five hundred and eighty (580) patients were randomised to the sham PO-FMD group and 576 to the PO-FMD group. Cannulation failure was reduced with PO-FMD, with cannulation failure rates of 2.7% in the PO-FMD group and 5.8% in the sham PO-FMD group (p=0.01).The number of puncture attempts was reduced with the use of PO-FMD, with a median of one attempt in the PO-FMD group and two in the sham PO-FMD group (p<0.001). Radial artery pulsation loss (RAPL) was reduced with PO-FMD, with 1.4% in the PO-FMD group and 3.8% in the sham PO-FMD group (p=0.02).
conclusionsPO-FMD reduces cannulation failure rates, decreases puncture attempts, and decreases RAPL during transradial coronary angiography.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.