Evidence map›Paper›PMID 31746487›Full record

ArticleMagnetic resonance in medicine2020

Improved volumetric myelin imaging in human brain using 3D dual echo inversion recovery-prepared UTE with complex echo subtraction.

Hyungseok Jang, Zhao Wei, Mei Wu, Ya-Jun Ma, Eric Y Chang, Jody Corey-Bloom, Jiang Du

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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  9. To measure TJournal of magnetic resonance (San Diego, Calif. : 1997) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hyungseok JangDepartment of Radiology, University of California San Diego, San Diego, California.ORCID 0000-0002-3597-9525
Zhao WeiDepartment of Radiology, University of California San Diego, San Diego, California.
Mei WuDepartment of Radiology, University of California San Diego, San Diego, California.ORCID 0000-0003-0952-5973
Ya-Jun MaDepartment of Radiology, University of California San Diego, San Diego, California.ORCID 0000-0003-0830-9232
Eric Y ChangDepartment of Radiology, University of California San Diego, San Diego, California.
Jody Corey-BloomDepartment of Neurosciences, University of California, San Diego, California.
Jiang DuDepartment of Radiology, University of California San Diego, San Diego, California.
University of California San Diego · US

Funding

Traning Clinical Scientists in Radiological ImagingT32EB005970 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Eric Y Chang, Rebecca Ann Rakow-Penner · 2007 to 2026
$3.2M
UTE Magnetic Resonance Imaging: New Biomarkers for Multiple SclerosisR01NS092650 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2015 to 2019
$1.9M
Quantitative Magnetic Resonance Imaging of Human Rotator Cuff TendonI01CX001388 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2016 to 2024
–
Quantitative Measurement of Joint pH with Magnetic Resonance ImagingI01RX002604 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2018 to 2022
–
CSRD VA I01 CX001388NIBIB NIH HHS T32 EB005970NINDS NIH HHS R01 NS092650RRD VA I01 RX002604
6 · The paper itself

Abstract

purposeInversion recovery-based UTE (IR-UTE) sequences have been proposed to directly image myelin with extremely short

methodsIn IR-UTE imaging, long T

resultsThe complex subtraction improved myelin contrast over the magnitude subtraction in both healthy and patient groups, with more fine myelin structures being revealed. The foci of the demyelinated lesion were more clearly detected by complex subtraction. An average signal enhancement of up to 135.9% was achieved with the complex subtraction over the magnitude subtraction.

conclusionThe complex echo subtraction improves 3D IR-UTE morphologic imaging of myelin in white matter of the brain.

Indexed as

Myelin SheathWhite MatterBrainGray MatterHumansImaging, Three-DimensionalMagnetic Resonance Imagingcomplex subtractioninversion recoverymagnitude subtractionmultiple sclerosismyelinUTE

Identifiers

PMID31746487
PMCPMC6949380
OpenAlexW2990906490

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.