Evidence map›Paper›PMID 31746186›Full record

ArticleEnvironmental science & technology2019

Exposure to Persistent Organic Pollutants (POPs) and Their Relationship to Hepatic Fat and Insulin Insensitivity among Asian Indian Immigrants in the United States.

Michele A La Merrill, Caitlin L Johnson, Martyn T Smith, Namratha R Kandula, Anthony Macherone, Kurt D Pennell, Alka M Kanaya

Open access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Municipal Solid Waste Management and Adverse Health Outcomes: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  2. Review
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  5. Article
  6. Article
  7. Obesity and Cardiovascular Risk among South Asian Americans.Current cardiovascular risk reports · 2023
    Article
  8. Review
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  10. Article
  11. Grandmaternal Perinatal Serum DDT in Relation to Granddaughter Early Menarche and Adult Obesity: Three Generations in the Child Health and Development Studies Cohort.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Michele A La MerrillDepartment of Environmental Toxicology , University of California , Davis , California 95616 , United States.ORCID http://orcid.org/0000-0002-5720-5862
Caitlin L JohnsonDepartment of Civil and Environmental Engineering , Tufts University , Medford , Massachusetts 02155 , United States.
Martyn T SmithDivision of Environmental Health Sciences, School of Public Health , University of California , Berkeley , California 94720 , United States.
Namratha R KandulaDepartments of Medicine and Preventive Medicine , Northwestern University Feinberg School of Medicine , Chicago , Illinois 60611 , United States.
Anthony MacheroneDivision of Life Science and Chemical Analysis , Agilent Technologies , Santa Clara , California 95051 , United States.
Kurt D PennellSchool of Engineering , Brown University , Providence , Rhode Island 02912 , United States.ORCID http://orcid.org/0000-0002-5788-6397
Alka M KanayaDepartments of Medicine, Epidemiology & Biostatistics , University of California , San Francisco , California 94115 , United States.
Agilent Technologies (United States) · USBrown University · USNorthwestern University · USTufts University · USUniversity of California, Berkeley · USUniversity of California, Davis · USUniversity of California, San Francisco · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI SMITH, MARTYN T · 1987 to 2025
$74.6M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Allison W Xu · 2015 to 2026
$14.6M
An environment-wide association study in autism spectrum disorders using novel bioinformatics methods and metabolomics via mass spectrometryR01MH107205 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI KONG, SEK WON · 2015 to 2019
$2.1M
Perinatal DDT causes insulin resistance in mice through impaired thermogenesisR01ES024946 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LA MERRILL, MICHELE A · 2016 to 2020
$1.9M
Ectopic fat and atherosclerosis in South AsiansK24HL112827 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2013 to 2022
$1.2M
Metabolic Syndrome and Atherosclerosis in South AsiansK23HL080026 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M. · 2006 to 2008
$442k
NCRR NIH HHS UL1 RR024131NHLBI NIH HHS K23 HL080026NHLBI NIH HHS K24 HL112827NIDDK NIH HHS P30 DK098722NIEHS NIH HHS P42 ES004705NIEHS NIH HHS R01 ES024946NIMH NIH HHS R01 MH107205
6 · The paper itself

Abstract

Persistent organic pollutants (POPs), such as dichlorodiphenyltrichloroethane (DDT) and other organochlorine compounds, are abundant in the environment and in foodstuffs from the Indian subcontinent. These environmental contaminants have been associated with a higher risk of diabetes in numerous studies. Asian Indians are well known to have a high risk of diabetes compared with other populations, and this risk is also found in migrant populations of Asian Indians in the United States, Europe, and elsewhere. We hypothesized that high plasma concentrations of POPs in Asian Indian migrants are linked to a variety of diabetes-related pathologies and explored the mechanism for the induction of these effects. We measured 30 environmental pollutants in plasma samples obtained from 147 participants in the Metabolic syndrome and Atherosclerosis in South Asians Living in America pilot study using a gas chromatography-tandem mass spectrometry analytical method that uses less than 0.5 mL of plasma. We found that plasma levels of

Indexed as

Emigrants and ImmigrantsEnvironmental PollutantsAnimalsEuropeGas Chromatography-Mass SpectrometryHumansPilot ProjectsUnited StatesEnvironmental Pollutants

Identifiers

PMID31746186
PMCPMC6996970
OpenAlexW2989747339

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.