Evidence map›Paper›PMID 31746084›Full record

ArticleStem cells (Dayton, Ohio)2020

Chemical activation of the Piezo1 channel drives mesenchymal stem cell migration via inducing ATP release and activation of P2 receptor purinergic signaling.

Fatema Mousawi, Hongsen Peng, Jing Li, Sreenivasan Ponnambalam, Sébastien Roger, Hucheng Zhao, Xuebin Yang, Lin-Hua Jiang

Open access · bronzeAbstract read
In one paragraph

Article in Stem cells (Dayton, Ohio), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 109 citations in OpenAlex.

  1. Article
  2. Piezo channels in tumors.Journal of cancer research and clinical oncology · 2026
    Review
  3. Article
  4. Review
  5. Article
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  7. Article
  8. Review
  9. Article
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  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Pharmacology of PIEZO1 channels.British journal of pharmacology · 2024
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Fatema MousawiSchool of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Hongsen PengSchool of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Jing LiLingnan Medical Research Centre, School of Medicine, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Sreenivasan PonnambalamSchool of Molecular and Cell Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Sébastien RogerEA4245, Transplantation, Immunology and Inflammation, Faculty of Medicine, University of Tours, Tours, France.
Hucheng ZhaoInstitute of Biomechanics and Medical Engineering, Tsinghua University, Beijing, People's Republic of China.
Xuebin YangDepartment of Oral Biology, Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.
Lin-Hua JiangSchool of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.ORCID 0000-0001-6398-0411
University of Leeds · GBUniversité de Tours · FRGuangzhou University of Chinese Medicine · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we examined the Ca

Indexed as

Adenosine TriphosphateAdultCell MovementChildFemaleHumansIon ChannelsMaleMesenchymal Stem CellsReceptors, Purinergic P2Signal TransductionYoung AdultAdenosine TriphosphateIon ChannelsPIEZO1 protein, humanReceptors, Purinergic P2ATP releaseMEK/ERKP2 receptorPiezo1 channelPYK2

Identifiers

PMID31746084
PMCPMC7064961
OpenAlexW2990067021

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.