Evidence map›Paper›PMID 31745828›Full record

ReviewCurrent environmental health reports2019

The Impact of Early-Life Exposure to Antimicrobials on Asthma and Eczema Risk in Children.

Medina S Jackson-Browne, Noelle Henderson, Marisa Patti, Adam Spanier, Joseph M Braun

Abstract readReview
In one paragraph

Review in Current environmental health reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. The Presence of Triclosan in Human Hair Samples in Poland-A Pilot Study.International journal of environmental research and public health · 2022
    Article
  14. Effect of triclosan on the pathogenesis of allergic diseases among children.Journal of exposure science & environmental epidemiology · 2022
    Article
  15. Article
  16. Article
  17. Increased Prevalence of Atopic Dermatitis in Children Aged 0-3 Years Highly Exposed to Parabens.International journal of environmental research and public health · 2021
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Medina S Jackson-BrowneEpidemiology Program, College of Health Sciences, University of Delaware, 100 Discovery Blvd, 7th floor, Newark, DE, USA. mjbrowne@udel.edu.
Noelle HendersonDepartment of Epidemiology, Brown University, Providence, RI, USA.
Marisa PattiDepartment of Epidemiology, Brown University, Providence, RI, USA.
Adam SpanierDepartment of Pediatrics, Division of General Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA.
Joseph M BraunDepartment of Epidemiology, Brown University, Providence, RI, USA.
Brown University · USUniversity of Delaware · USUniversity of Maryland, Baltimore · US

Funding

The Impact of Gestational and Postnatal Triclosan Exposure on Eczema, Wheeze, and Asthma Risk in ChildrenF32ES029812 · NIEHS · BROWN UNIVERSITY · PI JACKSON-BROWNE, MEDINA SAMIRA · 2019 to 2019
$19k
NIEHS NIH HHS F32 ES029812
6 · The paper itself

Abstract

purpose of reviewWe examined recent research on associations of prenatal and early-childhood exposure to the antimicrobial compounds, triclosan, and parabens, with the risk of asthma and eczema in children. We will discuss potential biological mechanisms of this association and highlight strengths and limitations of the study design and exposure assessment of current findings. RECENT

findingsResults of available toxicological and epidemiologic studies indicate a potential link of triclosan and paraben exposures with asthma and eczema in children, as well as changes in microbiome diversity and immune dysfunction, which could possibly mediate an association with the health outcomes. A small number of studies suggest that triclosan and paraben exposures could be related to the risk of asthma and eczema in children. Although current findings are far from conclusive, there is emerging evidence that changes in microbiome diversity and immune function from antimicrobial exposure may mediate these relations.

Indexed as

Anti-Infective AgentsAsthmaChildChild, PreschoolEczemaFemaleHumansMaleMaternal ExposureParabensPregnancyPrenatal Exposure Delayed EffectsTriclosanAnti-Infective AgentsParabensTriclosanAsthmaChildren’s healthEczemaImmune systemParabensTriclosan

Identifiers

PMID31745828
PMCPMC6923583
OpenAlexW2989746311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.