Evidence map›Paper›PMID 31745825›Full record

ArticleClinical journal of gastroenterology2020

Congestive hepatopathy and acute pancreatitis as severe complications of mixed connective tissue disease.

Shigekazu Kurihara, Takefumi Kimura, Naoki Tanaka, Takumi Yanagisawa, Hiroyuki Kobayashi, Keita Kanai, Takeji Umemura, Mamoru Kobayashi, Hiromitsu Mori, Shuichi Wada

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In one paragraph

Article in Clinical journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Shigekazu KuriharaDepartment of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Takefumi KimuraDepartment of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan. kimuratakefumii@yahoo.co.jp.
Naoki TanakaDepartment of Metabolic Regulation, Research Center for Agricultural Food Industry, Shinshu University School of Medicine, Shinshu University, Matsumoto, Japan.
Takumi YanagisawaDepartment of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Hiroyuki KobayashiDepartment of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Keita KanaiDepartment of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Takeji UmemuraDepartment of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Mamoru KobayashiDepartment of Nephrology, Nagano Red Cross Hospital, Nagano, Japan.
Hiromitsu MoriDepartment of Gastroenterology, Nagano Red Cross Hospital, Nagano, Japan.
Shuichi WadaDepartment of Gastroenterology, Nagano Red Cross Hospital, Nagano, Japan.
Shinshu University · JPNagano Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mixed connective tissue disease (MCTD) causes multiple organ dysfunctions, such as joint swelling, pulmonary fibrosis and hypertension, and serositis, but hepatopancreatic complications are rare. Here, we report a case of young man who exhibited acute severe liver dysfunction. He also had impaired cardiac function: both ventriculi were hypokinetic, but pulmonary hypertension and pericarditis were not observed. Since his liver and cardiac function markedly improved after commencing furosemide and carperitide, we considered congestive hepatopathy due to MCTD and accompanying heart failure. Heart failure and congestive hepatopathy recurred and he was treated with diuretics and prednisolone, but he passed away by co-occurrence of acute hemorrhagic pancreatitis. Necropsy revealed chronic hepatic congestion but not accompanying autoimmune hepatitis and hepatic vasculitis. We should consider congestive hepatopathy and hemorrhagic pancreatitis as serious complications of MCTD.

Indexed as

AdultFatal OutcomeHeart FailureHumansLiverLiver DiseasesMaleMixed Connective Tissue DiseasePancreatitisSkinTomography, X-Ray ComputedAutoimmune hepatitisCongestive hepatopathyHeart failureMixed connective tissue diseasePancreatitis

Identifiers

PMID31745825
OpenAlexW2990860728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.