Evidence map›Paper›PMID 31745739›Full record

ArticleMikrochimica acta2019

Ovalbumin antibody-based fluorometric immunochromatographic lateral flow assay using CdSe/ZnS quantum dot beads as label for determination of T-2 toxin.

Zhiwei Qie, Wenliang Yan, Zichen Gao, Wu Meng, Rui Xiao, Shengqi Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  7. Rapid, Quantitative, High-Sensitive Detection ofFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhiwei QieBeijing Institute of Radiation Medicine, Beijing, 100850, People's Republic of China.
Wenliang YanBeijing Institute of Radiation Medicine, Beijing, 100850, People's Republic of China.
Zichen GaoCenter for Diseases Prevention and Control of Rocket Force, Beijing, China.
Wu MengCenter for Diseases Prevention and Control of Rocket Force, Beijing, China.
Rui XiaoBeijing Institute of Radiation Medicine, Beijing, 100850, People's Republic of China. ruixiao203@sina.com.
Shengqi WangBeijing Institute of Radiation Medicine, Beijing, 100850, People's Republic of China. sqwang@bmi.ac.cn.
Beijing Radiation Center · CNState Council of the People's Republic of China · CN

Funding

ajor Infectious Diseases such as AIDS and Viral Hepatitis Prevention and Control Technology Major Projects 2018ZX10712-001the Major Projects No. AWS16J020
6 · The paper itself

Abstract

This work describes an anti-ovalbumin antibody-based lateral flow immunoassay (LFI) for T-2 toxin. The antibody uses a coating antigen as a bifunctional element for universality and introduces preincubation to improve the detection limits of the method. T-2 toxin and ovalbumin-modified T-2 toxin competitively binds on the anti-T-2 toxin monoclonal antibody modified on CdSe/ZnS quantum dot beads during preincubation. The modified T-2 toxin acts as a bifunctional element that forms immuno complexes during preincubation and combines with anti-ovalbumin antibody coated in the test line through the ovalbumin terminal. Fluorescence is detected at 610 nm on the test zone following photoexcitation at 365 nm. It has a reverse dose-effect relationship with the amount of T-2 toxin. The calibration plot is linear in the 20-110 fg mL

Indexed as

FluorometryImmunoassayAntibodiesCadmium CompoundsOvalbuminParticle SizeQuantum DotsSelenium CompoundsSulfidesSurface PropertiesT-2 ToxinZinc CompoundsAntibodiesCadmium Compoundscadmium selenideOvalbuminSelenium CompoundsSulfidesT-2 ToxinZinc Compoundszinc sulfideAflatoxin B1Bifunctional elementCalibration plotFluorometryLimit of detectionPreincubationSensitivity

Identifiers

PMID31745739
OpenAlexW2990548253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.