Evidence map›Paper›PMID 31745688›Full record

ArticleDigestive diseases and sciences2020

Afro-Caribbeans Have a Lower Prevalence of Advanced Colon Neoplasia than African-Americans.

Jose Melendez-Rosado, Katia Rodriguez, Harjinder Singh, Kiranmayee Kandragunta, Adalberto Gonzalez, Fayssa Salomon, Ishtiaq Hussain, Kanwarpreet Tandon, Fernando J Castro

Abstract readComparative StudyMulticenter StudyValidation Study
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In one paragraph

Article in Digestive diseases and sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jose Melendez-RosadoDepartment of Gastroenterology, Cleveland Clinic, 2950 Cleveland Clinic Blvd., Weston, FL, 33331, USA.
Katia RodriguezDepartment of Gastroenterology, Cleveland Clinic, 2950 Cleveland Clinic Blvd., Weston, FL, 33331, USA.
Harjinder SinghDepartment of Gastroenterology, Cleveland Clinic, 2950 Cleveland Clinic Blvd., Weston, FL, 33331, USA.
Kiranmayee KandraguntaDepartment of Gastroenterology, Cleveland Clinic, 2950 Cleveland Clinic Blvd., Weston, FL, 33331, USA.
Adalberto GonzalezDepartment of Gastroenterology, Cleveland Clinic, 2950 Cleveland Clinic Blvd., Weston, FL, 33331, USA.
Fayssa SalomonDepartment of Gastroenterology, Cleveland Clinic, 2950 Cleveland Clinic Blvd., Weston, FL, 33331, USA.
Ishtiaq HussainDepartment of Gastroenterology, Cleveland Clinic, 2950 Cleveland Clinic Blvd., Weston, FL, 33331, USA.
Kanwarpreet TandonDepartment of Gastroenterology, Cleveland Clinic, 2950 Cleveland Clinic Blvd., Weston, FL, 33331, USA.
Fernando J CastroDepartment of Gastroenterology, Cleveland Clinic, 2950 Cleveland Clinic Blvd., Weston, FL, 33331, USA. castrof@ccf.org.ORCID 0000-0001-8108-5402
Cleveland Clinic Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe black population in the USA is a heterogeneous group composed of smaller subgroups from different origins. The definition of black in many colorectal cancer (CRC) risk studies is vague, and differences in CRC risk comparing black subpopulations have not been evaluated. The aim of the study is to compare advanced colorectal neoplasia (ACN) between two subgroups of black populations: African-American (AA) and Afro-Caribbean (AC). A secondary aim was to determine whether there are differences in prevalence of adenomas.

methodsThis was a retrospective study of 3797 AA and AC patients undergoing first time screening colonoscopy in two different institutions in the USA.

resultsOverall adenoma prevalence was 29.3% for the entire population with 29.5% in AAs and 29.0% in AC with no statistically significant difference between the study groups (AOR: 1.02; 95% CI 0.88-1.18, P = 0.751). However, ACN was significantly higher in the AA group (11.8%) compared to AC (9.0%) (AOR: 1.30, 95% CI 1.02-1.66, P = 0.034). It was observed that AAs had ACN at a higher BMI than AC. After adjusting for BMI/ethnicity interactions, the difference in ACN between both groups became more significant (AOR: 1.93, 95% CI 1.16-3.23, P = 0.012).

conclusionsAAs have a higher risk of ACN than AC. Current recommendations to start screening in average-risk AAs at an earlier age may not apply to other black subgroups.

Indexed as

AdenomaAgedBlack or African AmericanCaribbean RegionColonic NeoplasmsFemaleFloridaHumansMaleMiddle AgedOhioPrevalenceRetrospective StudiesAfrican-AmericansAfro-CaribbeansColorectal cancer screeningColorectal neoplasiaMinorities

Identifiers

PMID31745688
OpenAlexW2990675637

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.