Evidence map›Paper›PMID 31745495›Full record

ArticleOptica2018

Handheld Adaptive Optics Scanning Laser Ophthalmoscope.

Theodore DuBose, Derek Nankivil, Francesco LaRocca, Gar Waterman, Kristen Hagan, James Polans, Brenton Keller, Du Tran-Viet, Lejla Vajzovic, Anthony N Kuo and 3 more

Open access · goldAbstract read
In one paragraph

Article in Optica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
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  4. Biomedical optics express · 2024
    Article
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  19. Article
  20. Advances in multimodal imaging in ophthalmology.Therapeutic advances in ophthalmology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Theodore DuBoseDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Derek NankivilDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Francesco LaRoccaDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Gar WatermanDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Kristen HaganDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
James PolansDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Brenton KellerDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Du Tran-VietDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, 27710, USA.
Lejla VajzovicDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, 27710, USA.
Anthony N KuoDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, 27710, USA.
Cynthia A TothDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, 27710, USA.
Joseph A IzattDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Sina FarsiuDepartment of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Duke University · USDuke Medical Center · US

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Vadim Y Arshavsky · 1985 to 2026
$19.3M
Handheld Portable Adaptive Optics Scanning Laser Ophthalmoscope for Imaging Young ChildrenR21EY027086 · NEI · DUKE UNIVERSITY · PI FARSIU, SINA, IZATT, JOSEPH A · 2016 to 2017
$425k
NEI NIH HHS P30 EY005722NEI NIH HHS R21 EY027086
6 · The paper itself

Abstract

Adaptive optics scanning laser ophthalmoscopy (AOSLO) has enabled in vivo visualization and enhanced understanding of retinal structure and function. Current generation AOSLOs have a large footprint and are mainly limited to imaging cooperative adult subjects. To extend the application of AOSLO to new patient populations, we have designed the first portable handheld AOSLO (HAOSLO) system. By incorporating a novel computational wavefront sensorless AO algorithm and custom optics, we have miniaturized our HAOSLO to weigh less than 200 grams. HAOSLO imaged the cones closest to the fovea with a handheld probe in adults and captured the first AO-enhanced image of cones in infants.

Identifiers

PMID31745495
PMCPMC6863352
OpenAlexW2888530845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.