Evidence map›Paper›PMID 31745397›Full record

ReviewInternational journal of health sciences

Efficacy of treatment methods for uncontrolled hypertension and its effects on atrial fibrillation: A systematic narrative review.

Abdulaziz A Alodhayani, Abdullah Alkhushail, Mashhor Alhantoushi, Saad M Alsaad, Turky H Almigbal, Khalid Alotaibi, Mohammed A Batais, Abdulrahman Altheaby, Sultan Al Dalbhi, Yasser Alghamdi

Open access · greenAbstract readReview
In one paragraph

Review in International journal of health sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Renal arteries denervation: from the treatment of resistant hypertension to the treatment of atrial fibrillation.European heart journal supplements : journal of the European Society of Cardiology · 2021
    Article
  2. Renal denervation: can we press the "ON" button again in 2020?Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Abdulaziz A AlodhayaniDepartment of Community and Family Medicine, King Saud University Medical City, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Abdullah AlkhushailPrince Sultan Cardiac Center, Riyadh, Saudi Arabia.
Mashhor AlhantoushiDepartment of Family Medicine, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia.
Saad M AlsaadDepartment of Community and Family Medicine, King Saud University Medical City, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Turky H AlmigbalDepartment of Community and Family Medicine, King Saud University Medical City, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Khalid AlotaibiDepartment of Clinical Pharmaceutical Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Mohammed A BataisDepartment of Community and Family Medicine, King Saud University Medical City, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Abdulrahman AltheabyDepartment of Hepatobiliary Sciences and Organ Transplant, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Sultan Al DalbhiDepartment of Clinical Pharmaceutical Services, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Yasser AlghamdiDepartment of Family Medicine, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia.
Prince Mohammed bin Abdulaziz Hospital · SAPrince Sultan University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesUncontrolled hypertension is a main predisposing risk factor leading to chronic atrial fibrillation (AF). Although several treatment methods for patients with HTN and AF were developed in past decades, further investigations of their efficacies are needed. This systematic narrative review presents an overview of studies reporting treatment efficacies in patients with HTN and/or AF.

methodsA narrative-based systematic review was performed using EMBASE, Medline, PubMed, Google Scholar, and the Cochrane Library searching for relevant papers published between October 2008 and October 2018. Out of 4481 studies, only 15 studies could be included following the inclusion criteria.

resultsIncluded studies reported treatment measures, measured outcomes, and efficacies in adult patients with HTN and AF with defined interventions and methodologies. Treatment methods with effective outcomes were administration of hydrochlorothiazide, losartan or atenolol, telmisartan or amlodipine, or general anti-hypertensive drugs. Treatment methods that showed the most effective outcomes (lowering AF recurrence and improving BP control) were those containing pulmonary vein (or antrum) isolation (PVI/PVAI) (6 studies) and/or in conjunction with renal denervation (RDN)(6 studies). Treatment methods showing the most effective outcomes were PVI/PVAI in conjunction with RDN.

conclusionThe latest evidence shows that PVI (in conjunction with RDN in some instances) was more efficacious among patients suffering from HTN and/or AF.

Indexed as

Atrial fibrillationtreatment methodsuncontrolled hypertension

Identifiers

PMID31745397
PMCPMC6852498
OpenAlexW2987838369

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.