Evidence map›Paper›PMID 31745253›Full record

ReviewBone marrow transplantation2020

Clinical practice recommendations for the diagnosis and management of human herpesvirus-6B encephalitis after allogeneic hematopoietic stem cell transplantation: the Japan Society for Hematopoietic Cell Transplantation.

Masao Ogata, Naoyuki Uchida, Takahiro Fukuda, Kazuhiro Ikegame, Tomohiko Kamimura, Makoto Onizuka, Koji Kato, Hikaru Kobayashi, Yoji Sasahara, Masashi Sawa and 5 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Bone marrow transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Masao OgataDepartment of Hematology, Oita University Hospital, Oita, Japan. mogata@oita-u.ac.jp.ORCID http://orcid.org/0000-0002-4896-5878
Naoyuki UchidaDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Takahiro FukudaHematopoietic Stem Cell Transplantation Division, National Cancer Center Hospital, Tokyo, Japan.
Kazuhiro IkegameDivision of Hematology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
Tomohiko KamimuraDepartment of Hematology, Harasanshin Hospital, Fukuoka, Japan.
Makoto OnizukaDepartment of Hematology and Oncology, Tokai University School of Medicine, Kanagawa, Japan.
Koji KatoDepartment of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science, Fukuoka, Japan.
Hikaru KobayashiDepartment of Hematology, Nagano Red Cross Hospital, Nagano, Japan.
Yoji SasaharaDepartment of Pediatrics, Tohoku University Graduate School of Medicine, Miyagi, Japan.
Masashi SawaDepartment of Hematology and Oncology, Anjo Kosei Hospital, Aichi, Japan.
Akihisa SawadaDepartment of Hematology/Oncology, Osaka Women's and Children's Hospital, Osaka, Japan.
Daiichiro HasegawaDepartment of Hematology/Oncology, Hyogo Prefectural Kobe Children's Hospital, Hyogo, Japan.
Masayoshi MasukoDivision of Stem Cell Transplantation, Niigata University Medical and Dental Hospital, Niigata, Japan.
Toshihiro MiyamotoDepartment of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science, Fukuoka, Japan.
Shinichiro OkamotoDivision of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactivation of human herpesvirus (HHV)-6B is relatively common after allogeneic hematopoietic stem cell transplantation (HSCT) and HHV-6B diseases may consequently develop. Among them, HHV-6B encephalitis is a serious and often fatal complication. The aim of these clinical practice recommendations is to provide diagnostic and therapeutic guidance for HHV-6B encephalitis after allogeneic HSCT. In this evidence-based review, we critically evaluated data from the published literature. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was used to assist in generating recommendations. We have summarized the findings that contribute to decision-making and we have provided our recommendations. In cases where rigorous clinical data are unavailable, recommendations have been developed in discussions with physicians who have relevant expertize.

Indexed as

EncephalitisEncephalitis, ViralHematopoietic Stem Cell TransplantationHerpesvirus 6, HumanRoseolovirus InfectionsHumansJapanTransplantation, Homologous

Identifiers

PMID31745253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.