Evidence map›Paper›PMID 31745219›Full record

ArticleScientific reports2019

Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26.

Bogdan Mitran, Helge Thisgaard, Sara Rinne, Johan Hygum Dam, Frishta Azami, Vladimir Tolmachev, Anna Orlova, Ulrika Rosenström

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Emerging Theranostic Radiometals (Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  4. A true theranostic pair -European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Article
  6. Article
  7. Unveiling the potential of copper-61 vs. gallium-68 for SSTR PET imaging.European journal of nuclear medicine and molecular imaging · 2025
    Article
  8. Article
  9. Article
  10. Controlling the Redox Chemistry of Cobalt Radiopharmaceuticals.Angewandte Chemie (International ed. in English) · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Scientific reports · 2021
    Article
  16. Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Bogdan MitranDepartment of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
Helge ThisgaardPET & Cyclotron Unit, Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Sara RinneDepartment of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
Johan Hygum DamPET & Cyclotron Unit, Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0001-6577-7011
Frishta AzamiDepartment of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
Vladimir TolmachevDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0002-6122-1734
Anna OrlovaDepartment of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-6120-2683
Ulrika RosenströmDepartment of Medicinal Chemistry, Uppsala University, Uppsala, Sweden. ulrika.rosenstrom@ilk.uu.se.
Uppsala University · SEUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrin-releasing peptide receptors (GRPRs) are promising targets in oligometastatic prostate cancer. We have recently used

Indexed as

AnimalsApoptosisBombesinCell ProliferationChelating AgentsCobalt RadioisotopesHumansMacrocyclic CompoundsMaleMiceMice, Inbred BALB CMice, Inbred NODMice, NudeMice, SCIDNeurotransmitter AgentsOrganometallic CompoundsBombesinChelating AgentsCobalt RadioisotopesMacrocyclic CompoundsNeurotransmitter AgentsOrganometallic CompoundsReceptors, Bombesin

Identifiers

PMID31745219
PMCPMC6863848
OpenAlexW2990805329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.