ArticleNature communications2019
Genetic evidence for assortative mating on alcohol consumption in the UK Biobank.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 69 citations in OpenAlex.
- Alcohol Consumption Is Associated with Poor Prognosis in Obese Patients with COVID-19: A Mendelian Randomization Study Using UK Biobank.Nutrients · 2021Trial
- Parental haplotype reconstruction in up to 440,209 UK and Estonian individuals reveals recent assortative mating dynamics.Nature human behaviour · 2026Article
- The mediation effect of sleep quality on the association between ambient air pollution and type 2 diabetes among UK adults: a population-based cohort study.BMC public health · 2025Article
- Criteria for detection of married or cohabiting couples in the UK Biobank.Social science & medicine (1982) · 2025Article
- Associations of Romantic Partners' Characteristics with Alcohol Consumption and Binge Drinking: Examining Evidence for Gene-Environment Interaction.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- A comparison of partner resemblance trends across putative same-sex and opposite-sex couples in the UK biobank.Scientific reports · 2025Article
- [Spousal correlations of blood lipid based on a family design].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Article
- Effects of childhood and adult height on later life cardiovascular disease risk estimated through Mendelian randomization.European journal of epidemiology · 2025Article
- Associations Between Having a Spouse/Partner with Alcohol Problems and One's Own Risk of Mental Health and Substance Use Disorders by Sexual Orientation.Substance use & misuse · 2025Article
- Mediating pathways between attention deficit hyperactivity disorder and type 2 diabetes mellitus: evidence from a two-step and multivariable Mendelian randomization study.Epidemiology and psychiatric sciences · 2024Article
- Whole exome sequencing analysis identifies genes for alcohol consumption.Nature communications · 2024Article
- A phenome-wide association and Mendelian randomisation study of alcohol use variants in a diverse cohort comprising over 3 million individuals.EBioMedicine · 2024Article
- An analysis of the accuracy of retrospective birth location recall using sibling data.Nature communications · 2024Article
- PheWAS-based clustering of Mendelian Randomisation instruments reveals distinct mechanism-specific causal effects between obesity and educational attainment.Nature communications · 2024Article
- Assortative mating and parental genetic relatedness contribute to the pathogenicity of variably expressive variants.American journal of human genetics · 2023Article
- Correlations in sleeping patterns and circadian preference between spouses.Communications biology · 2023Article
- The collaborative study on the genetics of alcoholism: Genetics.Genes, brain, and behavior · 2023Review
- Partner choice, confounding and trait convergence all contribute to phenotypic partner similarity.Nature human behaviour · 2023Article
- Spousal concordance in adverse childhood experiences and the association with depressive symptoms in middle-aged and older adults: findings across China, the US, and Europe.Frontiers in public health · 2023Article
- Assortative mating on blood type: Evidence from one million Chinese pregnancies.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Alcohol use is correlated within spouse-pairs, but it is difficult to disentangle effects of alcohol consumption on mate-selection from social factors or the shared spousal environment. We hypothesised that genetic variants related to alcohol consumption may, via their effect on alcohol behaviour, influence mate selection. Here, we find strong evidence that an individual's self-reported alcohol consumption and their genotype at rs1229984, a missense variant in ADH1B, are associated with their partner's self-reported alcohol use. Applying Mendelian randomization, we estimate that a unit increase in an individual's weekly alcohol consumption increases partner's alcohol consumption by 0.26 units (95% C.I. 0.15, 0.38; P = 8.20 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.