SynthesisSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
Safety of endoscopic retrograde cholangiopancreatography (ERCP) in pregnancy: A systematic review and meta-analysis.
Synthesis in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Laparoscopic bile duct exploration during pregnancy: a multi-center case series and literature review.Langenbeck's archives of surgery · 2023Pooled it
- Remimazolam versus propofol in combination with esketamine for surgical abortion: A double-blind randomized controlled trial.Clinical and translational science · 2023Trial
- ERCP during pregnancy: A 10-year experience from a tertiary care hospital in northern India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Laparoscopic management of cholelithiasis with choledocholithiasis in pregnancy: a case report.Annals of medicine and surgery (2012) · 2025Article
- Results of endoscopic retrograde cholangiopancreatography procedures at surgical clinics: A multicenter observational study in Türkiye.World journal of gastrointestinal surgery · 2025Article
- Modern Management of Common Bile Duct Stones: Breakthroughs, Challenges, and Future Perspectives.Cureus · 2024Review
- Investigating gastrointestinal disorders in pregnancy.Obstetric medicine · 2024Review
- Risk of Complications After Endoscopic Retrograde Cholangiopancreatography in Pregnancy: A Propensity-Matched Analysis.Digestive diseases and sciences · 2023Article
- Gastrointestinal malignancies in pregnancy.Abdominal radiology (New York) · 2023Review
- Surgery A survey of patients' perceptions and experiences of intervention for gallstone disease during pregnancy.Heliyon · 2022Article
- Management of Difficult Choledocholithiasis.Digestive diseases and sciences · 2022Review
- Management of common bile duct stones in a pregnant woman by percutaneous biliary drainage followed by elective endoscopic stone removal after delivery.BMJ case reports · 2022Article
- Choledocholithiasis in Pregnancy: A Case Report.Cureus · 2022Article
- The Clinical Application of Remimazolam Benzenesulfonate Combined with Esketamine Intravenous Anesthesia in Endoscopic Retrograde Cholangiopancreatography.BioMed research international · 2022Article
- Differences in Outcome and Comparison of Stress and Immune Status in Patients with Recurrent Common Bile Duct Stones after Biliary Tract Surgery Choosing Three Procedures (ERCP, OCBDE, and LCBDE) for Treatment.Computational and mathematical methods in medicine · 2022Article
- Effect of Programmed Nursing Plan Based on Thinking Map Guidance Mode on Hemodynamics and Intestinal Function Recovery of Patients Undergoing Endoscopic Retrograde Cholangiopancreatography.Emergency medicine international · 2022Article
- Effectiveness of supraglottic ventilation by transtracheal catheter for painless ERCP.American journal of translational research · 2021Article
- Long-term follow-up after fetal radiation exposure during endoscopic retrograde cholangiopancreatography.Endoscopy international open · 2020Article
- Choledocholithiasis in pregnancy: When and how to perform ERCP?Endoscopy international open · 2020Article
- Is endoscopic retrograde cholangiopancreatography safe during pregnancy?Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsEndoscopic retrograde cholangiopancreatography (ERCP) is a technically challenging procedure rarely associated with severe postprocedure complications. Hormonal changes during pregnancy promote cholelithiasis, but there are limited clinical data available on the outcomes of ERCP in pregnant women. ERCP techniques without irradiation were recently introduced as potential alternative. We performed a systematic review and meta-analysis to assess the safety of ERCP in pregnancy and to compare outcomes of radiation versus nonradiation ERCP. MATERIALS AND
methodsA systematic search of PubMed, Medline/Ovid, Web of Science, and Google Scholar through April 18
resultsIn all, 27 studies reporting on 1,307 pregnant patients who underwent ERCP were identified. Median age was 27.1 years. All results were statistically significant (P < 0.01). The pooled event rate for overall adverse outcomes was 15.9% (95% CI = 0.132-0.191) in all studies combined, 17.6% (95% CI = 0.109-0.272) in nonradiation ERCP (NR-ERCP) subgroup and 21.6% (95% CI = 0.154-0.294) in radiation ERCP subgroup. There was no significant difference in the pooled event rate for fetal adverse outcomes in NR-ERCP 6.2% (95% CI = 0.027-0.137) versus 5.2% (95% CI = 0.026-0.101) in radiation ERCP group. There was no significant difference in maternal pregnancy-related adverse outcome event rate between NR-ERCP (8.4%) (95% CI = 0.038-0.173) and radiation ERCP (7.1%) (95% CI = 0.039-0.125). Maternal nonpregnancy-related adverse outcome event rate in NR-ERCP was 7.6% (95% CI = 0.038-0.145), which was half the event rate in radiation ERCP group of 14.9% (95% CI = 0.102-0.211).
conclusionsERCP done by experienced endoscopists is a safe procedure during pregnancy. Radiation-free techniques appear to reduce the rates of nonpregnancy-related complications, but not of fetal and pregnancy-related complications.
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