Evidence map›Paper›PMID 31744924›Full record

ArticlemBio2019

The Staphylococcus aureus Transcriptome during Cystic Fibrosis Lung Infection.

Carolyn B Ibberson, Marvin Whiteley

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 54 citations in OpenAlex.

  1. Trial
  2. Bridging bench and bedside: translational omics ofEuropean respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Discovery ofmBio · 2026
    Article
  4. GrowingInfection and immunity · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Phenotypic and genotypic correlates of the sodium bicarbonate-responsive phenotype among methicillin-resistant Staphylococcus aureus isolates from skin and soft-tissue infections.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2025
    Article
  13. Review
  14. Analysis of genetic requirements and nutrient availability forbioRxiv : the preprint server for biology · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Microbiology spectrum · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Carolyn B IbbersonSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Marvin WhiteleySchool of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA mwhiteley3@gatech.edu.
Cystic Fibrosis Foundation · USGeorgia Institute of Technology · US

Funding

Mechanisms of Pseudomonas aeruginosa virulence in polymicrobial wound infectionsR01GM116547 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI WHITELEY, MARVIN · 2016 to 2019
$1.2M
Bacterial regulatory evolution during adaptation to chronic infectionsR56HL142857 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI BROWN, SAMUEL PAUL · 2018 to 2018
$501k
NHLBI NIH HHS R56 HL142857NIGMS NIH HHS R01 GM116547
6 · The paper itself

Abstract

Laboratory models have been invaluable for the field of microbiology for over 100 years and have provided key insights into core aspects of bacterial physiology such as regulation and metabolism. However, it is important to identify the extent to which these models recapitulate bacterial physiology within a human infection environment. Here, we performed transcriptomics (RNA-seq), focusing on the physiology of the prominent pathogen

Indexed as

Gene Expression Regulation, BacterialTranscriptomeAdaptation, PhysiologicalCluster AnalysisComputational BiologyCystic FibrosisGene Expression ProfilingHigh-Throughput Nucleotide SequencingHumansMachine LearningMetabolic Networks and PathwaysStaphylococcal InfectionsStaphylococcus aureusVirulencecystic fibrosishuman infectionmachine learningRNA-seqStaphylococcus aureustranscriptomicsvirulencevirulence factors

Identifiers

PMID31744924
PMCPMC6867902
OpenAlexW2987587883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.