Evidence map›Paper›PMID 31744919›Full record

ArticlemBio2019

Enterococcus faecalis Enhances Expression and Activity of the Enterohemorrhagic Escherichia coli Type III Secretion System.

Elizabeth A Cameron, Vanessa Sperandio, Gary M Dunny

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. AnMicrobiology spectrum · 2026
    Article
  2. Review
  3. Article
  4. Heterogeneity and metabolic diversity amongMicrobiology spectrum · 2025
    Article
  5. Insights into ecology, pathogenesis, and biofilm formation ofMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. EnterohemorrhagicGut microbes
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Elizabeth A CameronDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Vanessa SperandioDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Gary M DunnyDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA dunny001@umn.edu.
The University of Texas Southwestern Medical Center · USUniversity of Minnesota · US

Funding

Quorum Sensing Regulation of EHEC Virulence GenesR37AI053067 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI VANESSA SPERANDIO · 2018 to 2026
$5.3M
SdiA regulation of EHEC virulenceR01AI077613 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SPERANDIO, VANESSA · 2009 to 2017
$3.4M
Tryptophan derivatives in EHEC pathogenesisR01AI114511 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SPERANDIO, VANESSA · 2015 to 2019
$2.3M
Functional genomics analysis of colonization and persistence of Enterococcus faecalis in the gastrointestinal tract.R01AI122742 · NIAID · UNIVERSITY OF MINNESOTA · PI DUNNY, GARY M · 2016 to 2020
$2.2M
Enterococcal Sex pheromones: impact on antibiotic resistance transfer and ecology of the gastrointestinal tract.R35GM118079 · NIGMS · UNIVERSITY OF MINNESOTA · PI DUNNY, GARY M · 2016 to 2020
$2.1M
Sugar Regulation of EHEC virulence - A1R56AI105135 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI MARESSO, ANTHONY W, SPERANDIO, VANESSA · 2018 to 2018
$499k
The role of the human gut microbiota in modulating virulence of Enterohemorrhagic E. coliF32AI126722 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI CAMERON, ELIZABETH A · 2016 to 2018
$174k
NIAID NIH HHS F32 AI126722NIAID NIH HHS R01 AI077613NIAID NIH HHS R01 AI114511NIAID NIH HHS R01 AI122742NIAID NIH HHS R37 AI053067NIAID NIH HHS R56 AI105135NIGMS NIH HHS R35 GM118079
6 · The paper itself

Abstract

The gut microbiota can significantly impact invading pathogens and the disease they cause; however, many of the mechanisms that dictate commensal-pathogen interactions remain unclear. Enterohemorrhagic

Indexed as

Gene Expression Regulation, BacterialBacterial ProteinsEnterococcus faecalisEnterohemorrhagic Escherichia coliHumansMicrobiotaSymbiosisTranscriptional ActivationType III Secretion SystemsVirulence FactorsBacterial ProteinsType III Secretion SystemsVirulence Factorsbacterial communicationcommensal pathogen interactionEHECgut microbiomevirulence regulation

Identifiers

PMID31744919
PMCPMC6867897
OpenAlexW2986877241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.