Evidence map›Paper›PMID 31744915›Full record

ArticlemBio2019

Multidrug Resistance in Neisseria gonorrhoeae: Identification of Functionally Important Residues in the MtrD Efflux Protein.

Mohsen Chitsaz, Lauren Booth, Mitchell T Blyth, Megan L O'Mara, Melissa H Brown

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Structural analysis of resistance-nodulation cell division transporters.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  6. Review
  7. Low Oxygen Concentration ReducesAntibiotics (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. RND pumps across the genusMicrobial genomics · 2023
    Article
  14. Review
  15. Article
  16. Transcriptional regulation of theMicrobiology (Reading, England) · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mohsen ChitsazCollege of Science and Engineering, Flinders University, Bedford Park, SA, Australia.ORCID 0000-0001-6016-7687
Lauren BoothResearch School of Chemistry, Australian National University, Canberra, ACT, Australia.ORCID 0000-0002-4924-5661
Mitchell T BlythResearch School of Chemistry, Australian National University, Canberra, ACT, Australia.ORCID 0000-0001-9371-6515
Megan L O'MaraResearch School of Chemistry, Australian National University, Canberra, ACT, Australia.ORCID 0000-0002-8764-1585
Melissa H BrownCollege of Science and Engineering, Flinders University, Bedford Park, SA, Australia melissa.brown@flinders.edu.au.ORCID 0000-0001-6461-7550
Australian National University · AUFlinders University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A key mechanism that

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsBacterial ProteinsGonorrheaHumansMembrane ProteinsMembrane Transport ProteinsMicrobial Sensitivity TestsModels, MolecularNeisseria gonorrhoeaeProtein ConformationStructure-Activity RelationshipAnti-Bacterial AgentsBacterial ProteinsMembrane ProteinsMembrane Transport ProteinsMtrD protein, Neisseria gonorrhoeaedrug transportefflux pumpsmolecular dynamics simulationsMtrCDE systemmultidrug resistanceNeisseria gonorrhoeaeresistance-nodulation-division

Identifiers

PMID31744915
PMCPMC6867893
OpenAlexW2985995347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.