ArticlePediatrics2019
Early-Life Predictors of Fetal Alcohol Spectrum Disorders.
Article in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Examining Behavioral Interventions for Infancy and Early Toddlerhood: A Systematic Review of Intervention Effects, Parameters, and Participants.Journal of autism and developmental disorders · 2026Pooled it
- Maternal gut and vaginal microbiota, alcohol use during pregnancy, and infant fetal alcohol spectrum disorder diagnosis in a South African cohort.medRxiv : the preprint server for health sciences · 2026Article
- Does a Biochemical Approach Facilitate the Diagnosis of Prenatal Alcohol Exposure and Fetal Alcohol Spectrum Disorder in Neonatal Period?International journal of molecular sciences · 2026Review
- Contribution of ferritin and zinc to adverse infant outcomes among pregnancies with prenatal alcohol exposure in South Africa.Reproductive toxicology (Elmsford, N.Y.) · 2024Article
- The Impact of Prenatal Alcohol Exposure on Longitudinal Growth, Nutritional Status, and Insulin-Like Growth Factor 1 in Early Childhood in Leyte, the Philippines.The Journal of pediatrics · 2024Article
- Machine learning approaches to the identification of children affected by prenatal alcohol exposure: A narrative review.Alcohol, clinical & experimental research · 2024Review
- Novel Interventions on Comorbidities in Patients with Fetal Alcohol Spectrum Disorder (FASD): An Integrative Review.Biomedicines · 2024Review
- Predicting fetal alcohol spectrum disorders in preschool-aged children from early life factors.Alcohol, clinical & experimental research · 2024Article
- Fetal Alcohol Spectrum Disorders and Inadequacy of Care: Importance of Raising Awareness in Clinical Practice.Children (Basel, Switzerland) · 2023Review
- Multifaceted case management during pregnancy is associated with better child outcomes and less fetal alcohol syndrome.Annals of medicine · 2023Article
- The Benefit of a Retrospective Pregnancy Anamnesis in Child and Adolescent Psychiatry: The Reliability of Maternal Self-Report during Childhood Development.Children (Basel, Switzerland) · 2023Article
- Relationship-based intervention for children who were prenatally alcohol exposed in South Africa.Research in developmental disabilities · 2023Article
- Alcohol-related dysmorphic features as predictors of neurodevelopmental delay in infants and preschool-aged children: Results from a birth cohort in Ukraine.Alcoholism, clinical and experimental research · 2022Article
- The prevalence of fetal alcohol spectrum disorders in rural communities in South Africa: A third regional sample of child characteristics and maternal risk factors.Alcoholism, clinical and experimental research · 2022Article
- The influence of maternal weight and alcohol exposure on infant physical characteristics and neurodevelopmental outcomes.Current research in toxicology · 2022Article
- The challenges and pitfalls of fetal alcohol spectrum disorders prevalence studies.Alcoholism, clinical and experimental research · 2021Article
- Gestational age and birth growth parameters as early predictors of fetal alcohol spectrum disorders.Alcoholism, clinical and experimental research · 2021Article
- Institutionalized Children and the Risk of Fetal Alcohol Spectrum Disorder (FASD); A Primer for Clinicians, Adoption Staff and Parents.Global pediatric health · 2021Review
- Fetal Alcohol Spectrum Disorder: Can We Change the Future?Alcoholism, clinical and experimental research · 2020Article
Corrections and comments
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Authors and funding
15 authors at 9 institutions in 2 countries.
Funding
Abstract
BACKGROUND AND
objectivesFetal alcohol spectrum disorders (FASD) comprise the continuum of disabilities associated with prenatal alcohol exposure. Although infancy remains the most effective time for initiation of intervention services, current diagnostic schemes demonstrate the greatest confidence, accuracy, and reliability in school-aged children. Our aims for the current study were to identify growth, dysmorphology, and neurodevelopmental features in infants that were most predictive of FASD at age 5, thereby improving the timeliness of diagnoses.
methodsA cohort of pregnant South African women attending primary health care clinics or giving birth in provincial hospitals was enrolled in the project. Children were followed longitudinally from birth to 60 months to determine their physical and developmental trajectories (
resultsGrowth restriction and total dysmorphology scores differentiated among children with and without FASD as early as 9 months (area under the receiver operating characteristic curve = 0.777;
conclusionsAssessment of a combination of growth, dysmorphology, and neurobehavioral characteristics allows for accurate identification of most children with FASD as early as 9 to 18 months.
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