Evidence map›Paper›PMID 31744550›Full record

ArticleVeterinary research2019

In vitro and in vivo effects of 3-bromopyruvate against Echinococcus metacestodes.

Qi Xin, Miaomiao Yuan, Huanping Li, Xiaoxia Song, Jun Lu, Tao Jing

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

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  15. EgGLUT1 Is Crucial for the Viability ofFrontiers in cellular and infection microbiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qi XinInstitute of Pathogenic Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Miaomiao YuanInstitute of Pathogenic Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Huanping LiInstitute of Pathogenic Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Xiaoxia SongInstitute of Pathogenic Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Jun LuInstitute of Pathogenic Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Tao JingInstitute of Pathogenic Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China. jtao@lzu.edu.cn.ORCID http://orcid.org/0000-0001-8166-0358
Lanzhou University · CNSun Yat-sen University · CN

Funding

lzujbky lzujbky-2018-90NSFC 81171632
6 · The paper itself

Abstract

While searching for novel anti-echinococcosis drugs, we have been focusing on glycolysis which is relied on by Echinococcus for energy production and intermediates for other metabolic processes. The aim of this study was to investigate the potential therapeutic implication of glycolytic inhibitors on Echinococcus. Our results demonstrate that at an initial concentration of 40 μM, all inhibitors of glycolysis used in the current experiment [3-bromopyruvate (3-BrPA), ornidazole, clorsulon (CLS), sodium oxamate and 2,6-dihydroxynaphthalene (NA-P

Indexed as

AnimalsAnticestodal AgentsEchinococcosisEchinococcus granulosusEchinococcus multilocularisFemaleMiceMice, Inbred BALB CPyruvatesAnticestodal AgentsbromopyruvatePyruvates

Identifiers

PMID31744550
PMCPMC6862786
OpenAlexW2990588880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.