ReviewBMC gastroenterology2019
Syphilitic hepatitis: a case report and review of the literature.
Review in BMC gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Imaging evaluation and management of liver infections: a multimodality review.Abdominal radiology (New York) · 2026Review
- Syphilis Infection Triggering Autoimmune Hepatitis.ACG case reports journal · 2026Article
- Incidence of syphilitic hepatitis among patients with neurosyphilis.Internal medicine journal · 2025Article
- Multiple liver metastases of unknown origin: A case report.World journal of gastrointestinal oncology · 2025Article
- Diagnostic Challenges in Concurrent Primary Biliary Cholangitis and Secondary Syphilis: A Case Report.Journal of community hospital internal medicine perspectives · 2025Article
- Syphilitic hepatitis in infants, the forgotten disease that hepatologists have to brush up on: from a case series to a revision of literature.European journal of pediatrics · 2024Review
- Article
- Secondary Syphilis Can Simultaneously Mimic Cholestatic Liver Injury and Glomerular Nephropathy.ACG case reports journal · 2024Article
- A Rare Case of Widely Disseminated Syphilis.Acta dermato-venereologica · 2024Article
- Article
- Making a Comeback: Syphilitic Hepatitis in a Patient with Late Latent Syphilis-Case Report and Review of the Literature.Pathogens (Basel, Switzerland) · 2022Article
- A Giant Syphilitic Gastric Ulcer.ACG case reports journal · 2022Article
- Article
- Autoimmune Hepatitis Induced after Treatment of Syphilitic Hepatitis.Journal of clinical and translational hepatology · 2022Article
- An Unusual Case of Syphilis With Abdominal Pain.Cureus · 2021Article
- Article
- Case Report: Syphilitic Hepatitis-A Rare and Underrecognized Etiology of Liver Disease With Potential for Misdiagnosis.Frontiers in medicine · 2021Article
- Syphilis Hepatitis Presenting as a Mimic of Primary Biliary Cholangitis.ACG case reports journal · 2020Article
- Authors response to correspondence regarding paper entitled Syphilitic hepatitis: a case report and review of the literature.BMC gastroenterology · 2020Review
- Management of syphilitic hepatitis.BMC gastroenterology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundSyphilis is a common disease that has been researched and focused on for many years, however, syphilitic hepatitis has not been well-recognized. We report this case of syphilitic hepatitis with intrahepatic cholestasis and liver granulomas to make a deeper impression. CASE PRESENTATION: A 47-year-old male was admitted with jaundice and rashes. The laboratory examination showed abnormal liver enzymes with significant increases in ALP and GGT but mild increases in ALT and AST. His HBV surface antigen was weakly positive, with negative HIV antibody, HCV antibody, and undetectable HBV DNA. The rapid plasma reagin test and the Treponema pallidum particle assay tests for Syphilis were both positive. Abdominal ultrasonography and magnetic resonance cholangiopancreatography revealed the normal biliary tract, liver, and spleen. The liver pathological examination showed cholangiocyte inflammation and micro-granulomas with coagulation necrosis. After 2 months of benzathine penicillin treatment, his liver enzyme decreased rapidly and remained normal after 1-year of follow-up.
conclusionsIncreased liver enzymes, intrahepatic cholestasis and liver granulomas with well-response to antibiotics may provide clues for the diagnosis of syphilitic hepatitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.