Evidence map›Paper›PMID 31744268›Full record

ArticleTurkish journal of haematology : official journal of Turkish Society of Haematology2020

Fulya Küçükcankurt, Yücel Erbilgin, Sinem Fırtına, Özden Hatırnaz Ng, Zeynep Karakaş, Tiraje Celkan, Ayşegül Ünüvar, Uğur Özbek, Müge Sayitoğlu

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of haematology : official journal of Turkish Society of Haematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Fulya Küçükcankurtİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0002-5345-9072
Yücel Erbilginİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0001-6969-6649
Sinem Fırtınaİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0002-3370-8545
Özden Hatırnaz Ngİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0001-7728-6527
Zeynep Karakaşİstanbul University Faculty of Medicine, Department of Pediatrics Hematology, İstanbul, Turkey
Tiraje Celkanİstanbul University-Cerrahpaşa Cerrahpaşa Faculty of Medicine, Department of Pediatric Hematology, İstanbul, TurkeyORCID 0000-0001-7287-1276
Ayşegül Ünüvarİstanbul University Faculty of Medicine, Department of Pediatrics Hematology, İstanbul, TurkeyORCID 0000-0002-4730-7697
Uğur Özbekİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, Turkey
Müge Sayitoğluİstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, İstanbul, TurkeyORCID 0000-0002-8648-213X
Istanbul University · TRAltınbaş University · TRIstanbul University-Cerrahpaşa · TRKent Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: PTEN/AKT pathway deregulations have been reported to be associated with treatment response in acute leukemia. This study examined pediatric T-cell acute lymphoblastic leukemia (T-ALL) samples for Materials and Methods: Fifty diagnostic bone marrow samples of childhood T-ALL cases were investigated for the hotspot regions of the Results: A total of five PTEN variations were found in three of the 50 T-ALL cases (6%). Three of the Conclusion: Targeted deep sequencing allowed us to detect both low-level variations and clonal diversity. Low-level

Indexed as

AdolescentChildChild, PreschoolFemaleHigh-Throughput Nucleotide SequencingHumansInfantInfant, NewbornMalePrecursor T-Cell Lymphoblastic Leukemia-LymphomaProto-Oncogene Proteins c-aktPTEN PhosphohydrolaseAKT1 protein, humanProto-Oncogene Proteins c-aktPTEN PhosphohydrolasePTEN protein, humanAKT1Next-generation sequencingPTENT-ALL

Identifiers

PMID31744268
PMCPMC7236415
OpenAlexW2990737741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.