Evidence map›Paper›PMID 31744234›Full record

ArticlePathogens (Basel, Switzerland)2019

Natalya Kraeva, Tereza Leštinová, Aygul Ishemgulova, Karolina Majerová, Anzhelika Butenko, Slavica Vaselek, Julia Bespyatykh, Arzuv Charyyeva, Tatiana Spitzová, Alexei Yu Kostygov and 4 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Catalase impairsVirulence · 2021
    Article
  6. Article
  7. Genome Analysis ofGenes · 2021
    Article
  8. Article
  9. TheFrontiers in cellular and infection microbiology · 2021
    Article
  10. Involvement ofFrontiers in cellular and infection microbiology · 2021
    Review
  11. Article
  12. Metabolic Changes ofPathogens (Basel, Switzerland) · 2020
    Article
  13. SuicidalPathogens (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Natalya KraevaLife Sciences Research Centre, Faculty of Science, University of Ostrava, 71000 Ostrava, Czech Republic.ORCID 0000-0001-9111-5265
Tereza LeštinováDepartment of Parasitology, Faculty of Science, Charles University, 12844 Prague, Czech Republic.
Aygul IshemgulovaLife Sciences Research Centre, Faculty of Science, University of Ostrava, 71000 Ostrava, Czech Republic.
Karolina MajerováDepartment of Parasitology, Faculty of Science, Charles University, 12844 Prague, Czech Republic.
Anzhelika ButenkoLife Sciences Research Centre, Faculty of Science, University of Ostrava, 71000 Ostrava, Czech Republic.
Slavica VaselekDepartment of Parasitology, Faculty of Science, Charles University, 12844 Prague, Czech Republic.ORCID 0000-0002-9105-7138
Julia BespyatykhFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0002-4408-503X
Arzuv CharyyevaLife Sciences Research Centre, Faculty of Science, University of Ostrava, 71000 Ostrava, Czech Republic.ORCID 0000-0002-3056-3109
Tatiana SpitzováDepartment of Parasitology, Faculty of Science, Charles University, 12844 Prague, Czech Republic.
Alexei Yu KostygovLife Sciences Research Centre, Faculty of Science, University of Ostrava, 71000 Ostrava, Czech Republic.ORCID 0000-0002-1516-437X
Julius LukešBiology Centre, Institute of Parasitology, Czech Academy of Sciences, 37005 České Budejovice (Budweis), Czech Republic.
Petr VolfDepartment of Parasitology, Faculty of Science, Charles University, 12844 Prague, Czech Republic.ORCID 0000-0003-1790-1123
Jan VotýpkaDepartment of Parasitology, Faculty of Science, Charles University, 12844 Prague, Czech Republic.ORCID 0000-0002-0552-9363
Vyacheslav YurchenkoLife Sciences Research Centre, Faculty of Science, University of Ostrava, 71000 Ostrava, Czech Republic.ORCID 0000-0003-4765-3263
Charles University · CZUniversity of Ostrava · CZFederal Medical-Biological Agency · RUSechenov University · RUUniversity of South Bohemia in České Budějovice · CZ

Funding

European Regional Development Fund CZ.02.1.01/0.0/ 0.0/16_019/0000759European Research Council CZ LL1601Grantová Agentura České Republiky 17-10656SGrantová Agentura, Univerzita Karlova UNCE 20472Russian Science Foundation 19-15- 00054
6 · The paper itself

Abstract

Protein phosphorylation/dephosphorylation is an important regulatory mechanism that controls many key physiological processes. Numerous pathogens successfully use kinases and phosphatases to internalize, replicate, and survive, modifying the host's phosphorylation profile or signal transduction pathways. Multiple phosphatases and kinases from diverse bacterial pathogens have been implicated in human infections before. In this work, we have identified and characterized the dual specificity protein/lipid phosphatase LmDUSP1 as a novel virulence factor governing

Indexed as

Leishmania infectionLmDUSP1virulence factor

Identifiers

PMID31744234
PMCPMC6969907
OpenAlexW2983036503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.