Evidence map›Paper›PMID 31744232›Full record

ArticleNutrients2019

Oxidative Status before and after Renal Replacement Therapy: Differences between Conventional High Flux Hemodialysis and on-Line Hemodiafiltration.

José Alberto Navarro-García, Elena Rodríguez-Sánchez, Jennifer Aceves-Ripoll, Judith Abarca-Zabalía, Andrea Susmozas-Sánchez, Laura González Lafuente, Teresa Bada-Bosch, Eduardo Hernández, Evangelina Mérida-Herrero, Manuel Praga and 2 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

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  14. Blood Thiol Redox State in Chronic Kidney Disease.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

José Alberto Navarro-GarcíaCardiorenal Translational Laboratory, Institute of Research i+12, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.
Elena Rodríguez-SánchezCardiorenal Translational Laboratory, Institute of Research i+12, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.ORCID 0000-0002-5020-949X
Jennifer Aceves-RipollCardiorenal Translational Laboratory, Institute of Research i+12, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.
Judith Abarca-ZabalíaCardiorenal Translational Laboratory, Institute of Research i+12, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.
Andrea Susmozas-SánchezCardiorenal Translational Laboratory, Institute of Research i+12, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.
Laura González LafuenteCardiorenal Translational Laboratory, Institute of Research i+12, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.
Teresa Bada-BoschService of Nephrology, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.
Eduardo HernándezService of Nephrology, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.
Evangelina Mérida-HerreroService of Nephrology, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.
Manuel PragaService of Nephrology, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.
Luis Miguel RuilopeCardiorenal Translational Laboratory, Institute of Research i+12, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.
Gema Ruiz-HurtadoCardiorenal Translational Laboratory, Institute of Research i+12, Hospital Universitario 12 de Octubre, 28021 Madrid, Spain.ORCID 0000-0003-3482-0915
Hospital Universitario 12 De Octubre · ESCentro de Investigación en Red en Enfermedades Cardiovasculares · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemodialysis patients experience high oxidative stress because of systemic inflammation and depletion of antioxidants. Little is known about the global oxidative status during dialysis or whether it is linked to the type of dialysis. We investigated the oxidative status before (pre-) and after (post-) one dialysis session in patients subjected to high-flux dialysis (HFD) or on-line hemodiafiltration (OL-HDF). We analyzed carbonyls, oxidized LDL (oxLDL), 8-hydroxy-2'-deoxyguanosine, and xanthine oxidase (XOD) activity as oxidative markers, and total antioxidant capacity (TAC), catalase, and superoxide dismutase activities as measures of antioxidant defense. Indices of oxidative damage (OxyScore) and antioxidant defense (AntioxyScore) were computed and combined into a global DialysisOxyScore. Both dialysis modalities cleared all markers (

Indexed as

Oxidative StressAgedAntioxidantsBiomarkersCross-Sectional StudiesFemaleHemodiafiltrationHumansInflammationKidney Failure, ChronicMaleMiddle AgedRenal DialysisAntioxidantsBiomarkersdialysishigh-flux dialysison-line hemodiafiltrationoxidative stress

Identifiers

PMID31744232
PMCPMC6893513
OpenAlexW2984904461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.