ReviewMolecules (Basel, Switzerland)2019
Spirocyclic Motifs in Natural Products.
Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed.
- Synthesis of Spiro-Bridged 3,4-Dihydrocoumarins Through an Organocatalytic Cascade Sequence Diels-Alder/Nucleophilic Ring Closing.Molecules (Basel, Switzerland) · 2026Article
- Recent Advances in the Synthesis of Spiroindolines: Catalytic Strategies, Stereoselectivity, and Synthetic Utility (2020-2025).Molecules (Basel, Switzerland) · 2026Review
- Article
- Mastering the potential of well-defined MLChemical science · 2026Article
- From alkynes to spiroindole δ-lactamsChemical science · 2026Article
- Photoinduced Selective Construction of Densely Functionalized Spirocyclic Ethers With Carbyne Equivalents.Angewandte Chemie (International ed. in English) · 2026Article
- Photoenzymatic catalysis enables enantioselective radical dearomative spirocyclization.Nature communications · 2025Article
- Hexafluoroisopropanol-Mediated Cascade Cyclization for Construction of α‑Amino-γ-spirolactones.JACS Au · 2025Article
- Annulative endoperoxidation of tetronates.Organic & biomolecular chemistry · 2025Article
- Enantioselective Michael Spirocyclization of Palladium Enolates.ACS catalysis · 2025Article
- Diastereoselective Synthesis and Biological Evaluation of Spiro[chromane-2,4'-pyrimidin]-2'(3'Molecules (Basel, Switzerland) · 2025Article
- SPA-PNN ligand for the kinetic resolution of carbocyclic and heterocyclic spiranes by asymmetric hydrogenation.Nature communications · 2025Article
- A Review of Approaches Developed for Spiroether Synthesis.Topics in current chemistry (Cham) · 2025Review
- Size-Programmable Matteson-Type Annulation: Construction of Spirocycles from Simple Cyclic Ketones.Angewandte Chemie (International ed. in English) · 2025Article
- Short Scalable Route to Bis-morpholine Spiroacetals and Oxazepane Analogues: Useful 3D-Scaffolds for Compound Library Assembly.The Journal of organic chemistry · 2025Article
- Copper-Catalyzed Cyclization and Alkene Transposition Cascade Enables a Modular Synthesis of Complex Spirocyclic Ethers.Journal of the American Chemical Society · 2025Article
- [3 + 2] Cycloaddition of thioformylium methylide with various arylidene-azolones in the synthesis of 7-thia-3-azaspiro[4.4]nonan-4-ones.Beilstein journal of organic chemistry · 2025Article
- Divergent functionalization of alkenes enabled by photoredox activation of CDFA and α-halo carboxylic acids.Chemical science · 2024Article
- Exploring the Reactivity of Rigid 1-Azadienes Derived from Methylene γ-Lactams. Applications to the Stereoselective Synthesis of Spiro-γ-Lactams.The Journal of organic chemistry · 2024Article
- Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders.Journal of the American Chemical Society · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Spirocyclic motifs are emerging privileged structures for drug discovery. They are also omnipresent in the natural products domain. However, until today, no attempt to analyze the structural diversity of various spirocyclic motifs occurring in natural products and their relative populations with unique compounds reported in the literature has been undertaken. This review aims to fill that void and analyze the diversity of structurally unique natural products containing spirocyclic moieties of various sizes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.