Evidence map›Paper›PMID 31744202›Full record

ArticlePharmaceutics2019

Efficient Delivery of Therapeutic siRNA by Fe

Lili Jin, Qiuyu Wang, Jiayu Chen, Zixiang Wang, Hongchuan Xin, Dianbao Zhang

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 77 citations in OpenAlex.

  1. Innovative nanoparticle strategies for treating oral cancers.Medical oncology (Northwood, London, England) · 2025
    Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. The landscape of nanoparticle-based siRNA delivery and therapeutic development.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Co-delivery of Siape1 and Melatonin byRecent patents on anti-cancer drug discovery · 2024
    Article
  12. Review
  13. Review
  14. Review
  15. Oral delivery of RNAi for cancer therapy.Cancer metastasis reviews · 2023
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lili JinSchool of Life Science, Liaoning University, Shenyang 110036, China.
Qiuyu WangSchool of Life Science, Liaoning University, Shenyang 110036, China.
Jiayu ChenDepartment of Stem Cells and Regenerative Medicine, Key Laboratory of Cell Biology, National Health Commission of China, and Key Laboratory of Medical Cell Biology, Ministry of Education of China, China Medical University, Shenyang 110122, China.
Zixiang WangSchool of Life Science, Liaoning University, Shenyang 110036, China.
Hongchuan XinQingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
Dianbao ZhangDepartment of Stem Cells and Regenerative Medicine, Key Laboratory of Cell Biology, National Health Commission of China, and Key Laboratory of Medical Cell Biology, Ministry of Education of China, China Medical University, Shenyang 110122, China.ORCID 0000-0001-7063-7742
Liaoning University · CNNational Health and Family Planning Commission · CNChinese Academy of Sciences · CN

Funding

Foundation of China Medical University XZR20160022National Natural Science Foundation of China 31071916National Natural Science Foundation of China 81703102Scientific Research Program for Public Welfare of Liaoning Province 20170022
6 · The paper itself

Abstract

The incidence of oral cancer is increasing due to smoking, drinking, and human papillomavirus (HPV) infection, while the current treatments are not satisfactory. Small interfering RNA (siRNA)-based therapy has brought hope, but an efficient delivery system is still needed. Here, polyethyleneimine (PEI)-modified magnetic Fe

Indexed as

BCL2BIRC5/surviviniron oxidemagnetic nanoparticleoral cancersiRNA delivery

Identifiers

PMID31744202
PMCPMC6921101
OpenAlexW2987442633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.