Evidence map›Paper›PMID 31744135›Full record

ArticleInternational journal of molecular sciences2019

Impressic Acid, a Lupane-Type Triterpenoid from

Sun Woo Jin, Hoa Thi Pham, Jae Ho Choi, Gi Ho Lee, Eun Hee Han, Young Ho Cho, Young Chul Chung, Young Ho Kim, Hye Gwang Jeong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Sun Woo JinCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Hoa Thi PhamCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Jae Ho ChoiCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Gi Ho LeeCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Eun Hee HanDrug & Disease Target Research Team, Division of Bioconvergence Analysis, Korea Basic Science Institute (KBSI), Cheongju 28119, Korea.
Young Ho ChoDepartment of Pharmaceutics & Biotechnology, College of Medical Engineering, Konyang University, Daejeon 35365, Korea.ORCID 0000-0002-4570-2159
Young Chul ChungDepartment of Food Science, International University of Korea, Jinju, 52833, Korea.
Young Ho KimCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.ORCID 0000-0002-7441-9459
Hye Gwang JeongCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.ORCID 0000-0002-8020-8914
Chungnam National University · KRInternational University of Korea · KRKonyang University · KRKorea Basic Science Institute · KR

Funding

National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) No. NRF-2017R1A2B4008966 and NRF-2017R1A4A1015860
6 · The paper itself

Abstract

Atherosclerosis is one of the most reported diseases worldwide, and extensive research and trials are focused on the discovery and utilizing for novel therapeutics. Nitric oxide (NO) is produced mainly by endothelial nitric oxide synthase (eNOS) and it plays a key role in regulating vascular function including systemic blood pressure and vascular inflammation in vascular endothelium. In this study hypothesized that Impressic acid (IPA), a component isolated from

Indexed as

AMP-Activated Protein KinasesCalcium-Calmodulin-Dependent Protein Kinase Type 2Cell AdhesionCell LineEleutherococcusEndothelium, VascularHumansIntercellular Adhesion Molecule-1NF-kappa BNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide Synthase Type IIIPentacyclic TriterpenesPhosphorylationProto-Oncogene Proteins c-aktSignal Transduction3,11-dihydroxylup-20(29)-en-28-oic acidAMP-Activated Protein KinasesCalcium-Calmodulin-Dependent Protein Kinase Type 2Intercellular Adhesion Molecule-1lupaneNF-kappa BNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide Synthase Type IIIPentacyclic TriterpenesProto-Oncogene Proteins c-aktTriterpenesTumor Necrosis Factor-alphaAMPKCAMKIIEndothelial cellseNOSimpressic acid

Identifiers

PMID31744135
PMCPMC6888592
OpenAlexW2983486992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.