Evidence map›Paper›PMID 31744077›Full record

ReviewPathogens (Basel, Switzerland)2019

Apoptosis, Autophagy, and Pyroptosis: Immune Escape Strategies for Persistent Infection and Pathogenesis of Classical Swine Fever Virus.

Sheng-Ming Ma, Qian Mao, Lin Yi, Ming-Qiu Zhao, Jin-Ding Chen

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. ProbioticVeterinary sciences · 2026
    Article
  3. Review
  4. Strategies of Classical Swine Fever Immune Evasion.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Classical Swine Fever: A Truly Classical Swine Disease.Pathogens (Basel, Switzerland) · 2020
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sheng-Ming MaCollege of Veterinary Medicine; South China Agricultural University; Guangzhou 510642, China.
Qian MaoCollege of Veterinary Medicine; South China Agricultural University; Guangzhou 510642, China.
Lin YiCollege of Veterinary Medicine; South China Agricultural University; Guangzhou 510642, China.
Ming-Qiu ZhaoCollege of Veterinary Medicine; South China Agricultural University; Guangzhou 510642, China.
Jin-Ding ChenCollege of Veterinary Medicine; South China Agricultural University; Guangzhou 510642, China.
Guangzhou Experimental Station · CNSouth China Agricultural University · CN

Funding

the National Key Research and Development Program of China; the Science and Technology Program of Guangdong Province Nos, 2016YFD0500700 and Nos.2017YFD0500600; Nos.2019B020211003
6 · The paper itself

Abstract

Classical swine fever (CSF) is a severe acute infectious disease that results from classical swine fever virus (CSFV) infection, which leads to serious economic losses in the porcine industry worldwide. In recent years, numerous studies related to the immune escape mechanism of the persistent infection and pathogenesis of CSFV have been performed. Remarkably, several independent groups have reported that apoptosis, autophagy, and pyroptosis play a significant role in the occurrence and development of CSF, as well as in the immunological process. Apoptosis, autophagy, and pyroptosis are the fundamental biological processes that maintain normal homeostatic and metabolic function in eukaryotic organisms. In general, these three cellular biological processes are always understood as an immune defense response initiated by the organism after perceiving a pathogen infection. Nevertheless, several viruses, including CSFV and other common pathogens such as hepatitis C and influenza A, have evolved strategies for infection and replication using these three cellular biological process mechanisms. In this review, we summarize the known roles of apoptosis, autophagy, and pyroptosis in CSFV infection and how viruses manipulate these three cellular biological processes to evade the immune response.

Indexed as

apoptosisautophagyclassical swine fever viruspathogenesispyroptosis

Identifiers

PMID31744077
PMCPMC6963731
OpenAlexW2983661409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.