Evidence map›Paper›PMID 31743648›Full record

ArticleACS chemical biology2019

Mechanisms of Incorporation for D-Amino Acid Probes That Target Peptidoglycan Biosynthesis.

Erkin Kuru, Atanas Radkov, Xin Meng, Alexander Egan, Laura Alvarez, Amanda Dowson, Garrett Booher, Eefjan Breukink, David I Roper, Felipe Cava and 3 more

Open access · hybridAbstract read
In one paragraph

Article in ACS chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 169 citations in OpenAlex.

  1. Article
  2. Article
  3. Mislocalization of PBPs inMicrobiology spectrum · 2026
    Article
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  6. Review
  7. Article
  8. Article
  9. Infection and immunity · 2026
    Article
  10. Article
  11. Peptidoglycan LD-Transpeptidases.Antibiotics (Basel, Switzerland) · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Inactivation of thebioRxiv : the preprint server for biology · 2025
    Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 5 countries.

Erkin KuruDepartment of Genetics , Harvard Medical School , Boston , Massachusetts 02115 , United States.
Atanas RadkovDepartment of Biochemistry and Biophysics , UCSF School of Medicine , San Francisco , California 94158 , United States.
Xin MengDepartment of Chemistry , Indiana University , Bloomington , Indiana 47405 , United States.
Alexander EganCentre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences , Newcastle University , Newcastle upon Tyne , NE2 4AX , United Kingdom.
Laura AlvarezDepartment of Molecular Biology , Umeå University , SE-901 87 , Umeå , Sweden.
Amanda DowsonSchool of Life Sciences , University of Warwick , Coventry , CV4 7AL , United Kingdom.
Garrett BooherDepartment of Molecular and Cellular Biochemistry , Indiana University , Bloomington , Indiana 47405 , United States.
Eefjan BreukinkDepartment of Chemistry , Utrecht University , 3584 CH , Utrecht , Netherlands.
David I RoperSchool of Life Sciences , University of Warwick , Coventry , CV4 7AL , United Kingdom.ORCID 0000-0003-0009-621X
Felipe CavaDepartment of Molecular Biology , Umeå University , SE-901 87 , Umeå , Sweden.
Waldemar VollmerCentre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences , Newcastle University , Newcastle upon Tyne , NE2 4AX , United Kingdom.
Yves BrunDepartment of Microbiology, Infectious Diseases, and Immunology , Faculty of Medicine, Université de Montréal , Montréal , Canada.
Michael S VanNieuwenhzeDepartment of Chemistry , Indiana University , Bloomington , Indiana 47405 , United States.ORCID 0000-0001-6093-5949
Indiana University Bloomington · USNewcastle University · GBUmeå University · SEUniversity of Warwick · GBHarvard University · USUniversité de Montréal · CAUniversity of California, San Francisco · USUtrecht University · NL

Funding

Medical Research Council MR/N002679/1Wellcome Trust 101824/Z/13/Z
6 · The paper itself

Abstract

Bacteria exhibit a myriad of different morphologies, through the synthesis and modification of their essential peptidoglycan (PG) cell wall. Our discovery of a

Indexed as

Amino AcidsBacillus subtilisCell WallCytoplasmEscherichia coliMolecular ProbesPeptidoglycanPeptidyl TransferasesAmino AcidsMolecular ProbesPeptidoglycanPeptidyl Transferases

Identifiers

PMID31743648
PMCPMC6929685
OpenAlexW2990459709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.