ArticleJournal of applied clinical medical physics2019
A simple knowledge-based tool for stereotactic radiosurgery pre-planning.
Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Efficient optimization of R50% when planning multiple cranial metastases simultaneously in single isocenter SRS/SRT.Journal of applied clinical medical physics · 2021Article
- The surface area effect: How the intermediate dose spill depends on the PTV surface area in SRS.Journal of applied clinical medical physics · 2021Article
- An analytical expression for R50% dependent on PTV surface area and volume: A cranial SRS comparison.Journal of applied clinical medical physics · 2021Article
- An analytical expression for R50% dependent on PTV surface area and volume: a lung SBRT comparison.Journal of applied clinical medical physics · 2020Article
- A physically meaningful relationship between R50% and PTV surface area in lung SBRT.Journal of applied clinical medical physics · 2020Article
- Effects of Institutional Experience on Plan Quality in Stereotactic Radiotherapy Using HyperArc for Brain Metastases.In vivo (Athens, Greece)Article
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Authors and funding
3 authors.
Funding
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Abstract
We studied the dosimetry of single-isocenter treatment plans generated to treat a solitary intracranial lesion using linac-based stereotactic radiosurgery (SRS). A common metric for evaluating SRS plan quality is the volume of normal brain tissue irradiated by a dose of at least 12 Gy (V12), which is important because multiple studies have shown a strong correlation between V12 and incidence of radiation necrosis. Unrealistic expectations for values of V12 can lead to wasted planning time. We present a model that estimates V12 without having to construct a full treatment plan. This model was derived by retrospectively analyzing 50 SRS treatment plans, each clinically approved for delivery using circular collimator cone arc therapy (CAT). Each case was re-planned for delivery via dynamic conformal arc therapy (DCAT), and then scaling arguments were used to extend dosimetric data to account for different prescription dose (PD) values (15, 18, 21, or 24 Gy). We determined a phenomenological expression for the total volume receiving at least 12 Gy (TV12) as a function of both planning target volume (PTV) and PD:
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