Trial reportIndoor air2020
HEPA filtration improves asthma control in children exposed to traffic-related airborne particles.
Trial report in Indoor air, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 59 citations in OpenAlex.
- Randomized Clinical Trial of Air Cleaners to Improve Indoor Air Quality and Chronic Obstructive Pulmonary Disease Health: Results of the CLEAN AIR Study.American journal of respiratory and critical care medicine · 2022Trial
- Randomized trial of a portable HEPA air cleaner intervention to reduce asthma morbidity among Latino children in an agricultural community.Environmental health : a global access science source · 2022Trial
- Health effects of air pollution on chronic respiratory diseases.The Korean journal of internal medicine · 2026Review
- A review of indoor air quality interventions and child neurobehavioral outcomes.Pediatric research · 2026Review
- Health Benefits of Air Purification: A Systematic Review.Environment & health (Washington, D.C.) · 2026Review
- Effectiveness of enhanced filtration interventions for improving indoor air quality in child-serving facilities.Frontiers in pediatrics · 2026Article
- Article
- Assessing public support for air pollution mitigation and control policies: health, socioeconomic, and ideological predictors in an overburdened and vulnerable region of the U.S.BMC public health · 2025Article
- "You can feel the fresh air … " Rural Alaska Native household perceptions of home air purifiers and health.International journal of circumpolar health · 2024Article
- The Prevention of House Dust Mite Allergies in Pediatric Asthma.Children (Basel, Switzerland) · 2024Review
- Article
- Portable Air Cleaner Usage and Particulate Matter Exposure Reduction in an Environmental Justice Community: A Pilot Study.Environmental health insights · 2024Article
- Immune-mediated disease caused by climate change-associated environmental hazards: mitigation and adaptation.Frontiers in science · 2024Article
- Social-environmental phenotypes of rapid cystic fibrosis lung disease progression in adolescents and young adults living in the United States.Environmental advances · 2023Article
- Built environment factors predictive of early rapid lung function decline in cystic fibrosis.Pediatric pulmonology · 2023Article
- Gene-environment interactions and their impact on human health.Genes and immunity · 2023Review
- The relationship between PM2.5 and the onset and exacerbation of childhood asthma: a short communication.Frontiers in pediatrics · 2023Article
- Associations between outdoor air pollutants and non-viral asthma exacerbations and airway inflammatory responses in children and adolescents living in urban areas in the USA: a retrospective secondary analysis.The Lancet. Planetary health · 2023Article
- Article
- Patterns and Predictors of Air Cleaner Adherence Among Adults with COPD.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Traffic-related airborne particles are associated with asthma morbidity. The aim of this study was to assess the impact of a high-efficiency particulate air (HEPA) filtration on the concentrations of traffic particles and the resultant effect on children with asthma. Forty-three children with asthma were enrolled in this double-blind, placebo-controlled crossover design. A HEPA air cleaner or a placebo "dummy" was placed in participants' homes for four weeks, interrupted by a one-month washout period, before crossing over to the other treatment arm for four weeks. Air sampling and health outcomes, including asthma control (ACQ) and quality of life (AQLQ) measures, were completed prior to and at the end of each treatment arm. Indoor concentrations of traffic particles were significantly reduced with the HEPA treatment but not with the "dummy" treatment. In participants with poorly controlled asthma and lower quality of life at baseline, ACQ and AQLQ scores were significantly improved (1.3 to 0.9, P = .003 and 4.9 to 5.5, P = .02, respectively) following the HEPA treatment. In this study, HEPA filtration is associated with improved clinical outcomes and quality of life measures in children with uncontrolled asthma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.