Evidence map›Paper›PMID 31743335›Full record

ArticlePLoS medicine2019

Defining a recovery-oriented cascade of care for opioid use disorder: A community-driven, statewide cross-sectional assessment.

Jesse L Yedinak, William C Goedel, Kimberly Paull, Rebecca Lebeau, Maxwell S Krieger, Cheyenne Thompson, Ashley L Buchanan, Tom Coderre, Rebecca Boss, Josiah D Rich and 1 more

Abstract read
In one paragraph

Article in PLoS medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  4. Observational
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  18. "Rapid Start" Treatment to End the (Other) Epidemic: Walking the Tightrope Without a Net.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  19. Article
  20. Opioid Overdose Deaths with Buprenorphine Detected in Postmortem Toxicology: a Retrospective Analysis.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jesse L YedinakDepartment of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States of America.ORCID 0000-0001-8250-5157
William C GoedelDepartment of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States of America.ORCID 0000-0002-2869-1048
Kimberly PaullExecutive Office of Health and Human Services, State of Rhode Island, Cranston, Rhode Island, United States of America.ORCID 0000-0001-9979-2199
Rebecca LebeauExecutive Office of Health and Human Services, State of Rhode Island, Cranston, Rhode Island, United States of America.
Maxwell S KriegerDepartment of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States of America.ORCID 0000-0001-9975-1610
Cheyenne ThompsonExecutive Office of Health and Human Services, State of Rhode Island, Cranston, Rhode Island, United States of America.
Ashley L BuchananDepartment of Pharmacy Practice, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island, United States of America.ORCID 0000-0002-4715-3456
Tom CoderreOffice of the Governor, State of Rhode Island, Providence, Rhode Island, United States of America.
Rebecca BossDepartment of Behavioral Healthcare, Developmental Disabilities and Hospitals, State of Rhode Island, Cranston, Rhode Island, United States of America.
Josiah D RichDepartment of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States of America.
Brandon D L MarshallDepartment of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States of America.ORCID 0000-0002-0134-7052

Funding

Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI Brandon David Lewis Marshall · 2018 to 2026
$23.4M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
NIGMS NIH HHS P20 GM125507NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

backgroundIn light of the accelerating and rapidly evolving overdose crisis in the United States (US), new strategies are needed to address the epidemic and to efficiently engage and retain individuals in care for opioid use disorder (OUD). Moreover, there is an increasing need for novel approaches to using health data to identify gaps in the cascade of care for persons with OUD. METHODS AND

findingsBetween June 2018 and May 2019, we engaged a diverse stakeholder group (including directors of statewide health and social service agencies) to develop a statewide, patient-centered cascade of care for OUD for Rhode Island, a small state in New England, a region highly impacted by the opioid crisis. Through an iterative process, we modified the cascade of care defined by Williams et al. for use in Rhode Island using key national survey data and statewide health claims datasets to create a cross-sectional summary of 5 stages in the cascade. Approximately 47,000 Rhode Islanders (5.2%) were estimated to be at risk for OUD (stage 0) in 2016. At the same time, 26,000 Rhode Islanders had a medical claim related to an OUD diagnosis, accounting for 55% of the population at risk (stage 1); 27% of the stage 0 population, 12,700 people, showed evidence of initiation of medication for OUD (MOUD, stage 2), and 18%, or 8,300 people, had evidence of retention on MOUD (stage 3). Imputation from a national survey estimated that 4,200 Rhode Islanders were in recovery from OUD as of 2016, representing 9% of the total population at risk. Limitations included use of self-report data to arrive at estimates of the number of individuals at risk for OUD and using a national estimate to identify the number of individuals in recovery due to a lack of available state data sources.

conclusionsOur findings indicate that cross-sectional summaries of the cascade of care for OUD can be used as a health policy tool to identify gaps in care, inform data-driven policy decisions, set benchmarks for quality, and improve health outcomes for persons with OUD. There exists a significant opportunity to increase engagement prior to the initiation of OUD treatment (i.e., identification of OUD symptoms via routine screening or acute presentation) and improve retention and remission from OUD symptoms through improved community-supported processes of recovery. To do this more precisely, states should work to systematically collect data to populate their own cascade of care as a health policy tool to enhance system-level interventions and maximize engagement in care.

Indexed as

Analgesics, OpioidClinical ProtocolsCross-Sectional StudiesDrug OverdoseHumansNaltrexoneNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersRhode IslandRisk AssessmentRisk FactorsSocial WorkStakeholder ParticipationSubstance-Related DisordersUnited StatesAnalgesics, OpioidNaltrexoneNarcotic Antagonists

Identifiers

PMID31743335
PMCPMC6863520

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.