ArticleJournal of surgical oncology2020
Treatment of colorectal cancer in Sub-Saharan Africa: Results from a prospective Nigerian hospital registry.
Article in Journal of surgical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06630962 (Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care: A Randomized Control Trial- COST-FIN
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The efficacy of retrograde and antegrade enemas in the management of low anterior resection syndrome in patients undergoing rectal resection: a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Mortality rate and predictors of colorectal cancer patients in Ethiopia: a systematic review and meta-analysis.BMC cancer · 2024Pooled it
- Trial
- Colorectal Cancer Risk Factors in Adults in Nigeria.JAMA network open · 2026Article
- Evaluating clinicopathological pattern and management of colorectal cancer for adult patients presenting at Queen Elizabeth Central Hospital: a 10-year retrospective review.BMC gastroenterology · 2026Article
- Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care: A Randomized Control Trial- COST-FIN.Research square · 2026Article
- Prognostic factors and survival outcomes in colorectal cancer: insights from a Ghanaian cohort.BMC gastroenterology · 2025Article
- Understanding colorectal cancer-related stigma and its impact on cancer survivors in South-West Nigeria: a qualitative study of patients, caregivers, and healthcare professionals.Journal of cancer survivorship : research and practice · 2025Article
- The descriptive epidemiology of age at colorectal cancer diagnosis in Africa: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Rising Incidence and Mortality of Colorectal Cancer in Young African Adults: Need for a Better Care Plan.Cureus · 2025Review
- Immunohistochemical expression of PD-L1 in colorectal carcinoma among black patients and the clinicopathological correlates: a cross-sectional study.BMC gastroenterology · 2025Article
- Surgical outcomes research in LMICs: a narrative review.African health sciences · 2025Review
- Analysis of Risk Factors, Treatment Patterns, and Survival Outcomes After Emergency Presentation With Colorectal Cancer: A Prospective Multicenter Cohort Study in Nigeria.Journal of surgical oncology · 2025Article
- The financial burden of noncommunicable diseases from out-of-pocket expenditure in sub-Saharan Africa: a scoping review.Health promotion international · 2024Article
- Colorectal cancer disease profile and treatment patterns at an urban tertiary hospital in Rwanda.Ecancermedicalscience · 2024Article
- Inequities in global cancer surgery: Challenges and solutions.Journal of surgical oncology · 2024Review
- The African Research Group for Oncology: A decade fostering colorectal cancer research in Nigeria.Journal of surgical oncology · 2023Review
- Clinical presentation, treatment patterns, and outcomes of colorectal cancer patients at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia: A prospective cohort study.Cancer reports (Hoboken, N.J.) · 2023Article
- Demographic, clinical and pathological characterisation of patients with colorectal and anal cancer followed between 2013 and 2016 at Maputo Central Hospital, Mozambique.Ecancermedicalscience · 2021Article
- Article
Corrections and comments
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Authors and funding
27 authors.
Funding
Abstract
backgroundColorectal cancer (CRC) is the third most common cancer worldwide. Mortality for CRC is improving in high income countries, but in low and middle income countries, rates of disease and death from disease are rising. In Sub-Saharan Africa, the ratio of CRC mortality to incidence is the highest in the world. This study investigated the nature of CRC treatment currently being offered and received in Nigeria.
methodsBetween April 2013 and October 2017, a prospective study of consecutively diagnosed cases of CRC was conducted. Patient demographics, clinical features, and treatment recommended and received was recorded for each case. Patients were followed during the study period every 3 months or until death.
resultsThree hundred patients were included in our analysis. Seventy-one percent of patients received a recommended surgical operation. Of those that didn't undergo surgery as recommended, 37% cited cost as the main reason, 30% declined due to personal reasons, and less than 5% absconded or were lost to follow up. Approximately half of patients (50.5%) received a chemotherapy regimen when it was recommended, and 4.1% received radiotherapy when this was advised as optimal treatment. With therapy, the median overall survival for patients diagnosed with stage III and stage IV CRC was 24 and 10.5 months respectively. Overall, we found significantly better median survival for patients that received the recommended treatment (25 vs 7 months; P < .01).
conclusionsA number of patients were unable to receive the recommended treatment, reflecting some of the burden of untreated CRC in the region. Receiving the recommended treatment was associated with a significant difference in outcome. Improved healthcare financing, literacy, training, access, and a better understanding of tumor biology will be necessary to address this discrepancy.
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