Evidence map›Paper›PMID 31742649›Full record

ReviewActa dermato-venereologica2020

Psoriasis and Mental Health Workshop Report: Exploring the Links between Psychosocial Factors, Psoriasis, Neuroinflammation and Cardiovascular Disease Risk.

C Elise Kleyn, Peter S Talbot, Nehal N Mehta, Francesca Sampogna, Chris Bundy, Darren M Ashcroft, Alexa B Kimball, Peter C M van de Kerkhof, Christopher E M Griffiths, Fernando Valenzuela and 3 more

Abstract readReview
In one paragraph

Review in Acta dermato-venereologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. NasalJournal of inflammation research · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Impact of Mental State on the Severity of Psoriasis Symptoms: A Study on Patient's Emotional Well-Being.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Common Fundamentals of Psoriasis and Depression.Acta dermato-venereologica · 2021
    Article
  18. Article
  19. Article
  20. Dual inhibition of IL-17A and IL-17F in psoriatic disease.Therapeutic advances in chronic disease · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

C Elise KleynDermatology Centre, Salford Royal NHS Foundation Trust, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Peter S Talbot
Nehal N Mehta
Francesca Sampogna
Chris Bundy
Darren M Ashcroft
Alexa B Kimball
Peter C M van de Kerkhof
Christopher E M Griffiths
Fernando Valenzuela
Joelle M van der Walt
Tsion Aberra
Lluís Puig

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a systemic, relapsing, inflammatory disease associated with serious comorbidities including mood problems and/or unhealthy lifestyle behaviours. Cutaneous and systemic abnormalities in innate and acquired immunity play a role in its pathogenesis. The exact pathogenetic mechanism remains elusive. Evidence is accumulating that TNF-alpha, IL-17 and IL-23 signalling are highly relevant as targeting these pathways reduces disease activity. Evidence suggests a strong link between psoriasis and depression in adults. The International Psoriasis Council (IPC) held a roundtable event, "Psoriasis and Mental Health", in Barcelona, Spain which focused on the presence of depression and suicidality, plus the role of neuroinflammation in psoriasis, sleep disruption and the impact of depression on cardiovascular disease outcomes. We summarize here the expert presentations to provide additional insight into the understanding of psychiatric comorbidities of psoriasis and of the impact of chronic, systemic inflammation on neuro- and cardiovascular outcomes. the associations between psoriasis and other psychiatric comorbidities are still controversial and warrant further attention.

Indexed as

AdultCardiovascular DiseasesHumansInflammationMental HealthPsoriasisRisk Factorscardiovascular mental healthdepressionneuroinflammationpsoriasissleep

Identifiers

PMID31742649
PMCPMC9128964

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.