Evidence map›Paper›PMID 31742195›Full record

ArticleEuropean journal of case reports in internal medicine2019

Cerebral Venous Thrombosis and Acute Pulmonary Embolism following Varicella Infection.

Rashid Khan, Ajaz Yasmeen, Anoop Kumar Pandey, Khalid Al Saffar, Sunil Roy Narayanan

Open access · goldAbstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Atypical Varicella-Zoster Virus Reactivation: A Case Report.European journal of case reports in internal medicine · 2023
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Central nervous system infections produced by varicella zoster virus.Current opinion in infectious diseases · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rashid KhanDepartment of Internal Medicine, Belhoul Speciality Hospital, Dubai, UAE.
Ajaz YasmeenDepartment of Internal Medicine, Belhoul Speciality Hospital, Dubai, UAE.
Anoop Kumar PandeyDepartment of Radiology, Belhoul Speciality Hospital, Dubai, UAE.
Khalid Al SaffarDepartment of Neurology, Belhoul Speciality Hospital, Dubai, UAE.
Sunil Roy NarayananDepartment of Cardiology, Belhoul Speciality Hospital, Dubai, UAE.
Dubai Hospital · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varicella infection is caused by varicella-zoster virus (VZV) and commonly presents as a self-limiting skin manifestation in children. VZV also causes cerebral arterial vasculopathy and antibody-mediated hypercoagulable states leading to thrombotic complications in children, although there are very few such reports in adults. Postulated causal factors include vasculitis, direct endothelial damage, or acquired protein S deficiency secondary to molecular mimicry. These induced autoantibodies to protein S could lead to acquired protein S deficiency and produce a hypercoagulable state causing venous sinus thrombosis. Here we report the case of a 26-year-old man who presented with cortical venous sinus thrombosis and acute pulmonary embolism following varicella infection. Both conditions responded to anticoagulation treatment. LEARNING POINTS: Varicella infection caused by varicella-zoster virus (VZV) can rarely present with thrombotic complications after a period of latency.Postulated causal factors include vasculitis, direct endothelial damage, and acquired protein S deficiency secondary to molecular mimicry.The prognosis of post-varicella thrombosis is good, but a prothrombotic screen after recovery to diagnose hereditary prothrombotic states is advisable.

Indexed as

hypercoagulable stateprotein S deficiencypulmonary embolismvaricella infectionVenous thrombosis

Identifiers

PMID31742195
PMCPMC6822667
OpenAlexW2974505233

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.