Evidence map›Paper›PMID 31742165›Full record

ArticleJournal of family medicine and primary care2019

Study of antibiotic efficacy of topical vancomycin powder in treatment of infected mandibular fractures and soft tissue surgical site infections.

Geeta Singh, Deepak Passi, Deepti Daga, Abhigyan Manas, U Vignesh, Sujay Milind Bhave

Open access · goldAbstract read
In one paragraph

Article in Journal of family medicine and primary care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Effectiveness of combined local therapy with antibiotics and fibrin vs. vacuum-assisted wound therapy in soft tissue infections: a retrospective study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Geeta SinghDepartment of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, King Georges Medical University, Lucknow, Uttar Pradesh, India.
Deepak PassiDepartment of Dentistry, Sub-Divisional Hospital, Bundu, Ranchi, Jharkhand, India.
Deepti DagaDepartment of Head and Neck Oncology, Homi Bhabha Cancer Hospital, Varanasi, Uttar Pradesh, India.
Abhigyan ManasDepartment of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, King Georges Medical University, Lucknow, Uttar Pradesh, India.
U VigneshDepartment of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, King Georges Medical University, Lucknow, Uttar Pradesh, India.
Sujay Milind BhaveDepartment of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, King Georges Medical University, Lucknow, Uttar Pradesh, India.
King George's Medical University · INBhabha Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS AND

objectiveTo study the antibiotic efficacy of topical vancomycin in infected mandibular fracture treatment and its effect in preventing surgical site infections. MATERIALS AND

methodsThe study comprised of 100 subjects of infected mandibular fractures requiring open reduction and internal fixation, randomly categorized into two equal groups of 50 each, that is, vancomycin group (

resultsMean age of vancomycin group and non-vancomycin group was 32.5 and 33.2 years, respectively. Demographic factors of the patients like age, sex, and hospital stay (3 ± 0.5 days) did not show significant difference between two groups. Vancomycin group shows 1 hyperthermia, 2 abnormal swelling and discharge, whereas non-vancomycin group shows 6 hyperthermia, 5 postoperative abnormal swelling and discharge with statistically significant (

conclusionFrom the result of our study we can conclude that routine use of vancomycin powder in surgical site as a surgical adjunct reduces the incidence of infections at surgical site when it is applied in addition to standard antibiotic prophylaxis. Topical application into a surgical wound also reduces the risk associated with parenteral administration of vancomycin.

Indexed as

MRSA (Methicillin resistant Staphylococcus aureus)SSI (surgical site infections)systemic toxicityvancomycin

Identifiers

PMID31742165
PMCPMC6857408
OpenAlexW2982364664

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.