ArticleMultiple sclerosis journal - experimental, translational and clinical
Assessing fatigue in multiple sclerosis: Psychometric properties of the five-item Modified Fatigue Impact Scale (MFIS-5).
Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06064162 (A Pilot Study of Intravenous, Subanesthetic Dose of Ketamine Versus Placebo, A Crossover Design, for Multiple Sclerosis Related Fatigue), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Study of Intravenous, Subanesthetic Dose of Ketamine Versus Placebo, A Crossover Design, for Multiple Sclerosis Related Fatigue
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Measuring Fatigue in Multiple Sclerosis: A Rapid Review.The patient · 2025Pooled it
- Effectiveness of Motor Imagery on Motor Recovery in Patients with Multiple Sclerosis: Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Case Report: Improving gait and fatigue in multiple sclerosis through wearable electrical stimulation: a single-patient study.Frontiers in rehabilitation sciences · 2026Article
- Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation.Journal of medical Internet research · 2025Article
- Fatigue in Hemodialysis Patients: A Comparative Analysis with Healthy Controls.European journal of investigation in health, psychology and education · 2025Article
- Frequency and risk factors of sleep problems in Egyptian patients with multiple sclerosis.Frontiers in neurology · 2025Article
- Threatening illness perception and associated factors in early-stage relapsing-remitting multiple sclerosis.Frontiers in psychiatry · 2025Article
- Psychosocial Factors are Associated With Walking-Related Goal Attainment in Multiple Sclerosis: A Preliminary Study.International journal of MS care · 2025Article
- Factors affecting fatigue progression in multiple sclerosis patients.Scientific reports · 2024Article
- Motor function in multiple sclerosis assessed by navigated transcranial magnetic stimulation mapping.Journal of neurology · 2024Article
- Fatigue, Internet Addiction and Symptoms of Long COVID-A Cross-Sectional Study of Polish Students.Journal of clinical medicine · 2024Article
- Feasibility of Telerehabilitation-Monitored Functional Electrical Stimulation on Walking and Quality of Life in People With Multiple Sclerosis: A Case Series.International journal of MS care · 2024Article
- Decisional Conflict Regarding Disease-Modifying Treatment Choices Among Patients with Mid-Stage Relapsing-Remitting Multiple Sclerosis.Patient preference and adherence · 2024Article
- Fatigue and physical activity levels in poles living in Poland and the United Kingdom in the further year of the COVID-19 pandemic: a pilot study.BMC public health · 2023Article
- Fatigue and Physical Activity in People after COVID-19 in Poland.Journal of personalized medicine · 2023Article
- Hopelessness in Patients with Early-Stage Relapsing-Remitting Multiple Sclerosis.Patient preference and adherence · 2023Article
- Strengthening Mental Abilities with Relational Training (SMART) in multiple sclerosis (MS): study protocol for a feasibility randomised controlled trial.Pilot and feasibility studies · 2022Article
- Predicting Multiple Sclerosis Outcomes During the COVID-19 Stay-at-home Period: Observational Study Using Passively Sensed Behaviors and Digital Phenotyping.JMIR mental health · 2022Article
- Outcome measures assisting treatment optimization in multiple sclerosis.Journal of neurology · 2022Review
- Information-Seeking Strategies of People with Multiple Sclerosis in Spain: The INFOSEEK-MS Study.Patient preference and adherence · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fatigue in multiple sclerosis is a key symptom associated with work-related problems and poor quality of life outcomes. The five-item Modified Fatigue Impact Scale is a brief self-assessment tool for measuring the impact of fatigue on cognitive, physical and psychosocial function. A non-interventional, cross-sectional study was conducted to assess dimensionality and item characteristics of the five-item Modified Fatigue Impact Scale in multiple sclerosis. A total of 302 subjects were studied. Mokken analysis found the five-item Modified Fatigue Impact Scale is a strong one-dimensional scale (overall scalability index
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.