Evidence map›Paper›PMID 31741548›Full record

ArticleOrganometallics2019

Cross-Coupling and Related Reactions: Connecting Past Success to the Development of New Reactions for the Future.

Louis-Charles Campeau, Nilay Hazari

Abstract read
In one paragraph

Article in Organometallics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 475 citations in OpenAlex.

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  9. One-Pot Amidation/C─H Halogenation by an Efficient Electrochemical Cascade.Angewandte Chemie (International ed. in English) · 2026
    Article
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  18. Advances in NiACS catalysis · 2026
    Review
  19. Review
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Louis-Charles CampeauDepartment of Process Research and Development, Merck Research Laboratories, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Nilay HazariDepartment of Chemistry, Yale University, P.O. Box 208107, New Haven, Connecticut 06520, United States.ORCID 0000-0001-8337-198X
Merck & Co., Inc., Rahway, NJ, USA (United States) · USYale University · US

Funding

Mechanistic Studies to Rationally Design Ni and Pd Catalysts for Cross-CouplingR01GM120162 · NIGMS · YALE UNIVERSITY · PI HAZARI, NILAY · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM120162
6 · The paper itself

Abstract

Cross-coupling reactions, which were discovered almost 50 years ago, are widely used in both industry and academia. Even though cross-coupling reactions now represent mature technology, there is still a significant amount of research in this area that aims to improve the scope of these reactions, develop more efficient catalysts, and make reactions more practical. In this tutorial, a brief background to cross-coupling reactions is provided, and then the major advances in cross-coupling research over the last 20 years are described. These include the development of improved ligands and precatalysts for cross-coupling and the extension of cross-coupling reactions to a much wider range of electrophiles. For example, cross-coupling reactions are now common with sp

Identifiers

PMID31741548
PMCPMC6860378
OpenAlexW2902896374

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.