Evidence map›Paper›PMID 31741304›Full record

ArticleJournal of ultrasound2020

Surgical margin follow-up after nephron-sparing surgery: the possible role of CEUS.

Elena Bertelli, Laura Mercatelli, Elena Savi, Alessandro Pili, Silvia Verna, Alberto Palombella, Davide Caramella, Andrea Minervini, Sergio Serni, Simone Agostini and 1 more

Abstract read
In one paragraph

Article in Journal of ultrasound, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elena BertelliDepartment of Radiology, Careggi University Hospital, Florence, Italy. elena.bertelli3@gmail.com.ORCID http://orcid.org/0000-0001-5218-7733
Laura MercatelliDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Elena SaviDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Alessandro PiliDepartment of Urologic Robotic Surgery and Renal Transplantation, Careggi Hospital, University of Florence, Florence, Italy.
Silvia VernaDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Alberto PalombellaDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Davide CaramellaDiagnostic and Interventional Radiology, University of Pisa, Florence, Italy.
Andrea MinerviniDepartment of Urologic Robotic Surgery and Renal Transplantation, Careggi Hospital, University of Florence, Florence, Italy.
Sergio SerniDepartment of Urologic Robotic Surgery and Renal Transplantation, Careggi Hospital, University of Florence, Florence, Italy.
Simone AgostiniDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Vittorio MieleDepartment of Radiology, Careggi University Hospital, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the possible role of CEUS in the management of patients who underwent nephron-sparing surgery (NSS) and presented questionable findings on the surgical margins at the CECT follow-up exam.

methodsIn our retro-prospective study, we included 952 patients with small renal masses (SRMs) treated with NSS between 2012 and 2015 and followed with CECT for at least 3 years at Careggi University Hospital. Twenty-two of them presented solid masses on the site of surgery with questionable enhancement at CECT and were further studied with CEUS. This examination was followed by a quantitative analysis of the enhancement pattern.

resultsOut of the 22 masses, 18 were considered possible granulomas, presenting slow wash-in and low enhancement peaks compared to the surrounding parenchyma and persistent delayed wash-out at CEUS. Four lesions presented a suspicious malignant enhancement pattern, with rapid wash-in, high peak and rapid wash-out. In accordance with instructions from the urologist, the first group of 18 patients was strictly monitored, revealing that the mass dimensions and enhancement pattern were stable for at least 3 years of follow-up, while the other 4 patients underwent a second intervention and their masses were confirmed as tumor recurrence at the histopathological evaluation.

conclusionsCEUS can play a key role in the surgical margin follow-up after NSS when a suspicious enhancing mass is detected by CECT, giving an accurate depiction of the enhancement pattern and thus helping the clinician in the management of the patient.

Indexed as

Contrast MediaMargins of ExcisionFollow-Up StudiesGranulomaHumansKidney DiseasesKidney NeoplasmsNeoplasm Recurrence, LocalNephronsProspective StudiesRetrospective StudiesUltrasonographyContrast MediaCancerCEUSGranulomaKidneyNephron-sparing surgery (NSS)Small renal masses (SRM)

Identifiers

PMID31741304
PMCPMC7588569

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.