ReviewDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2019
A comprehensive review of clinical studies with herbal medicine on polycystic ovary syndrome (PCOS).
Review in Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07399535 (Clinical Investigation of Herbal Formulation and Its Efficacy in Polycystic Ovarian Syndrome), which is not on this map. Cited by 60 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Investigation of Herbal Formulation and Its Efficacy in Polycystic Ovarian Syndrome
Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it, 135 citations in OpenAlex.
- Chinese herbal medicine for subfertile women with polycystic ovarian syndrome.The Cochrane database of systematic reviews · 2021Pooled it
- Article
- Therapeutic effects of pomegranate hot-water extract via inhibition of apoptosis and oxidative stress in a DHEA-induced mouse model of PCOS.Integrative medicine research · 2026Article
- Ovarian aging: maintenance and activation of the primordial follicle pool.Journal of ovarian research · 2026Review
- Network Pharmacology Integrated Molecular Docking Analysis Identifies Potential Phytochemicals in Stachys lavandulifolia against Polycystic Ovary Syndrome.Current pharmaceutical design · 2026Article
- Efficacy of licorice extract in combination with a low-calorie diet on sex hormones, sleep quality, depression, and appetite in overweight/obese women with polycystic ovary syndrome: An RCT.International journal of reproductive biomedicine · 2026Article
- Effect of Xiaonang Yusi decoction () on IVF outcomes in patients with phlegm-dampness type PCOS: a prospective cohort study with supporting metabolomics, network pharmacology, and molecular docking analysis.Frontiers in medicine · 2026Article
- Safety and effectiveness of marjoram and cinnamon herbal tea supplementation in managing polycystic ovary syndrome: a pilot randomized, double-blind, controlled trial.Annals of medicine and surgery (2012) · 2025Article
- Network pharmacology-based investigation of potential targets of mulberry twig acting on polycystic ovary syndrome.Medicine · 2025Article
- Mechanism of Zuogui pill in the treatment of polycystic ovary syndrome based on LC-MS and proteomics.Journal of ovarian research · 2025Article
- Chinese herbal medicine on the offspring of women with polycystic ovary syndrome: A retrospective cohort study.Medicine · 2025Article
- Mechanism study on the regulation of autophagy and oxidative stress through SIRT1/PI3K/AKT pathway by Liuwei Dihuang pill to improve ovarian function.Journal of ovarian research · 2025Article
- Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management.Journal of health, population, and nutrition · 2025Review
- Large animal models in gynecology: status and future perspectives.Frontiers in veterinary science · 2025Review
- Role of Seed Therapy on Estrous and Non-Estrous Cycle in Healthy Female Rats.Food science & nutrition · 2025Article
- Beneficial Effects of Curcumin in Polycystic Ovary Syndrome: A Review of Recent Literature and Underlying Mechanisms.Current medicinal chemistry · 2025Review
- Comparative Study of Lactogenic Effect and Milk Nutritional Density of Oral Galactagogue in Female Rabbit.Current protein & peptide science · 2025Article
- Polycystic Ovary Syndrome and the Potential for Nanomaterial-Based Drug Delivery in Therapy of This Disease.Pharmaceutics · 2024Review
- The latest reports and treatment methods on polycystic ovary syndrome.Annals of medicine · 2024Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPolycystic ovary syndrome (PCOS) is a frequent medical condition characterized by both metabolic and reproductive disorders. Different pharmaceutical treatments have been proposed for PCOS. However, side effects of long-term treatments and their probable low efficacy have made complementary and alternative treatments a valuable option. Recent reports have indicated the increased use of complementary treatments. Herbal medicine, as part of complementary medicine, was find introduced in traditional Persian and Chinese medicine. Medicinal herbs have used for a long time in the treatment of gynecological and infertility problems of PCOS patients. In this study, we aimed to review herbal medicines used for PCOS worldwide.
methodsPubMed, Embase, Cochrane, and Scopus databases were searched for clinical trials and Randomized Controlled Trials based on related keywords. Data were collected from 1990 to 2019.
resultsAccording to a multitude of studies, a wide spectrum of herbs can be used to improve various aspects of PCOS. Herbs such as Cinnamomum verum, Trigonella foenum-graecum L., and Vitex agnus-castus can impact on menstrual and ovulatory dysfunctions, obesity, insulin resistance, lipid-metabolism dysfunction, and androgen excess-related conditions.
conclusionSome plants as natural remedies may have beneficial effects on improving different aspects of PCOS; but further studies are needed to investigate their mechanisms and safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.