Evidence map›Paper›PMID 31741262›Full record

ArticleMolecular biology reports2020

Sequence characteristics of Medicago truncatula cyclophilin family members and function analysis of MsCYP20-3B involved in axillary shoot development.

Lingqiao Ge, Kun Zhang, Xiaohui Cao, Yinyin Weng, Bei Liu, Peisheng Mao, Xiqing Ma

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Article in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lingqiao GeCollege of Grassland Science and Technology, China Agricultural University, Beijing, China.
Kun ZhangCollege of Grassland Science and Technology, China Agricultural University, Beijing, China.
Xiaohui CaoCollege of Grassland Science and Technology, China Agricultural University, Beijing, China.
Yinyin WengCollege of Grassland Science and Technology, China Agricultural University, Beijing, China.
Bei LiuCollege of Grassland Science and Technology, China Agricultural University, Beijing, China.
Peisheng MaoCollege of Grassland Science and Technology, China Agricultural University, Beijing, China.
Xiqing MaCollege of Grassland Science and Technology, China Agricultural University, Beijing, China. ma018@cau.edu.cn.ORCID http://orcid.org/0000-0002-8524-9037
China Agricultural University · CNBeijing Haidian Hospital · CN

Funding

Fundamental Research Funds for Central Universities of the Central University 2018QC144Fundamental Research Funds for Central Universities of the Central University NSFC
6 · The paper itself

Abstract

Cyclophilins (CYPs) belonging to the immunophilin family are present in all organisms and widely distributed in various cells associated with the activity of peptidyl-prolyl cis/trans isomerase. Plant CYPs are members of a multi-gene family and are involved in a series of biological processes. However, little is known about their structure, evolution, developmental expression and functional analysis in Medicago truncatula. In this study, a total of 33 CYP genes were identified and found to be unevenly distributed on eight chromosomes. Among them, 21 are single-domain and 12 are multi-domain proteins, and most were predicted to be localized in the cytosol, nucleus or chloroplast. Phylogenetic and gene structure analysis revealed seven segmental gene pairs, indicating that segmental duplication probably made a large contribution to the expansion of MtCYP gene family. Furthermore, gene expression analysis revealed that about 10 MtCYP genes (were) highly expressed involved in vegetative and reproduction tissues in M. truncatula, and MsCYP20-3B was mainly upregulated in stems, leaves and flower buds in alfalfa (Medicago sativa). Overexpression of MsCYP20-3B was shown to regulate axillary shoot development associated with higher jasmonic acid and abscisic acid contents in M. truncatula. Our study suggests the importance of the CYP genes family in development, reproduction and stress responses, and provides a reference for future studies and application of CYP genes for alfalfa genetic improvement.

Indexed as

ChloroplastsChromosomes, PlantCyclophilinsGene Expression ProfilingGene Expression Regulation, PlantGenes, PlantGenome, PlantMedicago truncatulaMultigene FamilyPlant LeavesPlant ProteinsCyclophilinsPlant ProteinsAlfalfaCyclophilin genesGene expression patternMedicago truncatulaPhylogenetic analysisTransgenic plants

Identifiers

PMID31741262
OpenAlexW2987380640

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.