Evidence map›Paper›PMID 31741153›Full record

Observational studySurgical endoscopy2020

Laparoscopic right hemicolectomy: the SICE (Società Italiana di Chirurgia Endoscopica e Nuove Tecnologie) network prospective trial on 1225 cases comparing intra corporeal versus extra corporeal ileo-colic side-to-side anastomosis.

Gabriele Anania, Ferdinando Agresta, Elena Artioli, Serena Rubino, Giuseppe Resta, Nereo Vettoretto, Wanda Luisa Petz, Carlo Bergamini, Alberto Arezzo, Giorgia Valpiani and 3 more

Erratum issued Registry-linked trialOpen access · hybridAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03934151 (Multicenter National Observational Study on Intracorporeal Versus Extracorporeal Technique for Ileocolic Anastomosis in Laparoscopic Right Hemicolectomy), which is not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03934151 completednot on this map

Multicenter National Observational Study on Intracorporeal Versus Extracorporeal Technique for Ileocolic Anastomosis in Laparoscopic Right Hemicolectomy

Typeobservational_patient_registrySponsorUniversity Hospital of FerraraRan2018 to 2018Enrolled1,225ConditionsComplication of Gastrointestinal Anastomosis, Intestinal Anastomosis ComplicationArmsintracorporeal ileocolic anastomosis, extracorporeal ileocolic anastomosis
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Gabriele AnaniaDivision of General Surgery, S. Anna University Hospital of Ferrara, via Aldo Moro 8, Cona, FE, Italy. g.anania@unife.it.ORCID 0000-0001-9255-3312
Ferdinando AgrestaDepartment of General Surgery, ULSS5 Polesana del Veneto, Adria, RO, Italy.
Elena ArtioliDivision of General Surgery, S. Anna University Hospital of Ferrara, via Aldo Moro 8, Cona, FE, Italy.
Serena RubinoDivision of General Surgery, S. Anna University Hospital of Ferrara, via Aldo Moro 8, Cona, FE, Italy.
Giuseppe RestaDivision of General Surgery, S. Anna University Hospital of Ferrara, via Aldo Moro 8, Cona, FE, Italy.
Nereo VettorettoMontichiari Surgery, ASST Spedali Civili Brescia, Montichiari, BS, Italy.
Wanda Luisa PetzDivision of Gastrointestinal Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Carlo BergaminiDepartment of Emergency Surgery, University Hospital of Careggi, Florence, Italy.
Alberto ArezzoDepartment of Surgical Sciences, University of Torino, Turin, Italy.
Giorgia ValpianiMsC in Statistics at Research Innovation Office, S. Anna University Hospital of Ferrara, Ferrara, Italy.
Chiara MorottiMsC in Statistics at Research Innovation Office, S. Anna University Hospital of Ferrara, Ferrara, Italy.
Gianfranco SilecchiaDepartment of Medical Surgical Science and Biotechnologies, Faculty Pharmacy and Medicine, Sapienza University of Rome, Rome, Italy.
SICE CoDIG (Colon Dx Italian Group)
University of Ferrara · ITAzienda Ospedaliero-Universitaria Careggi · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITSapienza University of Rome · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile laparoscopic approach for right hemicolectomy (LRH) is considered appropriate for the surgical treatment of both malignant and benign diseases of right colon, there is still debate about how to perform the ileo-colic anastomosis. The ColonDxItalianGroup (CoDIG) was designed as a cohort, observational, prospective, multi-center national study with the aims of evaluating the surgeons' attitude regarding the intracorporeal (ICA) or extra-corporeal (ECA) anastomotic technique and the related surgical outcomes.

methodsOne hundred and twenty-five Surgical Units experienced in colorectal and advanced laparoscopic surgery were invited and 85 of them joined the study. Each center was asked not to change its surgical habits. Data about demographic characteristics, surgical technique and postoperative outcomes were collected through the official SICE website database. One thousand two hundred and twenty-five patients were enrolled between March 2018 and September 2018.

resultsICA was performed in 70.4% of cases, ECA in 29.6%. Isoperistaltic anastomosis was completed in 85.6%, stapled in 87.9%. Hand-sewn enterotomy closure was adopted in 86%. Postoperative complications were reported in 35.4% for ICA and 50.7% for ECA; no significant difference was found according to patients' characteristics and technologies used. Median hospital stay was significantly shorter for ICA (7.3 vs. 9 POD). Postoperative pain in patients not prescribed opioids was significantly lower in ICA group.

conclusionsIn our survey, a side-to-side isoperistaltic stapled ICA with hand-sewn enterotomy closure is the most frequently adopted technique to perform ileo-colic anastomosis after any indications for elective LRH. According to literature, our study confirmed better short-term outcomes for ICA, with reduction of hospital stay and postoperative pain.

trial registrationClinical trial (Identifier: NCT03934151).

Indexed as

AgedAnastomosis, SurgicalColectomyColonColonic NeoplasmsFemaleHumansLaparoscopyMaleProspective StudiesTreatment OutcomeIleo-colic anastomosisIntracorporeal anastomosisLaparoscopyOutcomesPostoperative complicationsRight hemicolectomy

Identifiers

PMID31741153
PMCPMC7572335
OpenAlexW2982777464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.