ReviewCurrent atherosclerosis reports2019
Effects of Radiotherapy in Coronary Artery Disease.
Review in Current atherosclerosis reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 62 citations in OpenAlex.
- Ischemic heart disease and cardio-onco-hematology: a comprehensive review.Cardio-oncology (London, England) · 2026Review
- Cardiac magnetic resonance imaging AI-guided stereotactic arrhythmia radioablation for scar-related refractory ventricular tachycardia: a case report.Journal of geriatric cardiology : JGC · 2026Article
- Vascular Changes and Surgical Risk in Cervical vs. Endometrial Cancer After Radiotherapy: A Retrospective Cohort Study.Life (Basel, Switzerland) · 2026Article
- Impact of cancer treatments on coronary plaque as assessed by integrated backscatter intravascular ultrasound.Cardiology journal · 2026Article
- Risk of cardiovascular-related death after radiotherapy for thoracic cancer.Radiation oncology (London, England) · 2025Article
- Therapeutic Immunomodulation in Cardiovascular Disease: Anti-inflammatory Strategies and Landmark Trials.Cureus · 2025Review
- A Comprehensive Review of Radiotherapy-Induced Coronary Artery Disease-Epidemiology, Biological Mechanisms, and Preventive Strategies.International journal of molecular sciences · 2025Review
- Radiation-Induced Cardiotoxicity in Hypertensive Salt-Sensitive Rats: A Feasibility Study.Life (Basel, Switzerland) · 2025Article
- Radiotherapy Increases Carotid Intima-Media Thickness in Patients with Nasopharyngeal Carcinoma Compared to a Healthy Control Group: A 6-Year Follow-Up Study.Diagnostics (Basel, Switzerland) · 2025Article
- Exploring Resting Sinus Tachycardia in Cancer Care: A Comprehensive Review.Journal of clinical medicine · 2025Review
- Radiation-Induced Macrovessel/Microvessel Disease.Arteriosclerosis, thrombosis, and vascular biology · 2024Review
- Heart ultrasound and biomechanical evaluation of radiation-induced heart toxicity using transthoracic echocardiogram (TTE) and dynamic mechanical analysis (DMA).Precision radiation oncology · 2024Article
- Late coronary artery injury following chemoradiotherapy for thymic carcinoma: a case report.BMC cardiovascular disorders · 2024Article
- Risk and prognosis of secondary lung cancer after radiation therapy for thoracic malignancies.The clinical respiratory journal · 2024Article
- Early Development of Atherosclerotic Plaques in the Coronary Arteries after Radiotherapy for Breast Cancer (BACCARAT Study).Journal of cardiovascular development and disease · 2023Article
- An overview of radiation-induced heart disease.Radiation oncology journal · 2022Article
- Potential Role of Neutrophil Extracellular Traps in Cardio-Oncology.International journal of molecular sciences · 2022Review
- Cardiac inflammation and fibrosis following chemo/radiation therapy: mechanisms and therapeutic agents.Inflammopharmacology · 2022Review
- Radiation-induced cardiac dysfunction: Practical implications.Kardiologia polska · 2022Review
- Risk and prognosis of secondary bladder cancer after radiation therapy for pelvic cancer.Frontiers in oncology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThis review describes the effects of radiotherapy (RT) on coronary artery disease, its mechanisms, and clinical and laboratory evidence and discusses ways to minimize radiation-induced coronary atherosclerosis. RECENT
findingsRadiation-induced cardiac toxicity is known in patients undergoing thoracic RT. One of the damages occurs in the coronary arteries, with accelerated atherosclerosis manifesting decades later. There is clinical and laboratory evidence of coronary damage in retrospective studies, systematic reviews, and meta-analyses. Clinical studies have shown that RT cardiotoxicity occurs decades after radiation, regardless of chemotherapy, and may occur earlier in patients with pre-existing risk factors or disease. The pathogenesis of radiation-induced coronary artery disease is complex and multifactorial, including endothelial dysfunction, altered vascular tone, hemostatic imbalance, and inflammatory activation. Some factors are responsible, such as mean heart dose, RT chest site, patient position, techniques, and breathing maneuvers. There are approaches to reduce radiation-induced cardiac toxicity. Among them, besides the mentioned factors, metformin and anti-inflammatory agents can minimize coronary damage, with impact on morbidity and mortality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.