Evidence map›Paper›PMID 31741058›Full record

ReviewPharmaceutical research2019

Remote Controlled Autonomous Microgravity Lab Platforms for Drug Research in Space.

Shimon Amselem

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pharmaceutical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Deep space environment empowering drug design and development.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  4. Article
  5. Review
  6. Application of Microgravity Experiments in Plastic Surgery: A Literature Review.Plastic and reconstructive surgery. Global open · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Role of Apoptosis in Wound Healing and Apoptosis Alterations in Microgravity.Frontiers in bioengineering and biotechnology · 2021
    Review
  18. Article
  19. Review
  20. One Giant Leap for Pharmacology.Pharmaceutical research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Shimon AmselemSpacePharma R&D Israel LTD, 1st Aba Even Av, 4672519, Herzliya Pituach, Israel. amselem.shimon@space4p.com.ORCID http://orcid.org/0000-0003-0752-5451

Funding

Lung Host Defense in MicrogravityUG3TR002198 · NCATS · CHILDREN'S HOSP OF PHILADELPHIA · PI HUH, DONGEUN, WORTHEN, GEORGE SCOTT · 2017 to 2018
$1.4M
H2020 Industrial Leadership () 718717NCATS NIH HHS 1-UG3-TR-002198-01;1-UG3-TR- 002598-01Office of the Chief Scientist, Ministry of Health several grants
6 · The paper itself

Abstract

Research conducted in microgravity conditions has the potential to yield new therapeutics, as advances can be achieved in the absence of phenomena such as sedimentation, hydrostatic pressure and thermally-induced convection. The outcomes of such studies can significantly contribute to many scientific and technological fields, including drug discovery. This article reviews the existing traditional microgravity platforms as well as emerging ideas for enabling microgravity research focusing on SpacePharma's innovative autonomous remote-controlled microgravity labs that can be launched to space aboard nanosatellites to perform drug research in orbit. The scientific literature is reviewed and examples of life science fields that have benefited from studies in microgravity conditions are given. These include the use of microgravity environment for chemical applications (protein crystallization, drug polymorphism, self-assembly of biomolecules), pharmaceutical studies (microencapsulation, drug delivery systems, behavior and stability of colloidal formulations, antibiotic drug resistance), and biological research, including accelerated models for aging, investigation of bacterial virulence , tissue engineering using organ-on-chips in space, enhanced stem cells proliferation and differentiation.

Indexed as

WeightlessnessAge FactorsCell DifferentiationCell LineCell ProliferationCrystallizationDimerizationDrug CompoundingDrug Delivery SystemsDrug DiscoveryDrug Resistance, MicrobialHumansMicrofluidicsPharmaceutical ResearchPhysical PhenomenaProteinsProteinslab-on-chipsmicrogravity researchnanosatellitesorgan-on-chipsparabolic flights

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.