Evidence map›Paper›PMID 31741056›Full record

ArticleMikrochimica acta2019

SERS determination of the antihypertensive drugs prazosin and losartan by using silver nanoparticles coated with β-cyclodextrin.

Jiawei Wu, Hao Ma, Xiangfeng Bu, Chao Ma, Lin Zhu, Baoqin Hao, Bing Zhao, Yuan Tian

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiawei WuCollege of Chemistry, Jilin University, Changchun, 130012, People's Republic of China.
Hao MaState Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun, 130012, People's Republic of China.
Xiangfeng BuCollege of Chemistry, Jilin University, Changchun, 130012, People's Republic of China.
Chao MaState Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun, 130012, People's Republic of China.
Lin ZhuState Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun, 130012, People's Republic of China.
Baoqin HaoCollege of Chemistry, Jilin University, Changchun, 130012, People's Republic of China.
Bing ZhaoState Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun, 130012, People's Republic of China.
Yuan TianCollege of Chemistry, Jilin University, Changchun, 130012, People's Republic of China. tianyuan@jlu.edu.cn.ORCID 0000-0003-3105-8419

Funding

National Natural Science Foundation of China 21327803National Natural Science Foundation of China 21711540292National Natural Science Foundation of China 21773080Science-Technology Development Project of Jilin Province of China 20170101174JC
6 · The paper itself

Abstract

A surface-enhanced Raman scattering (SERS) method is described for the determination of prazosin (PRH) and losartan (LOS). Silver nanoparticles modified with β-cyclodextrin (CD-S-Ag NPs) were prepared and serve as a sensitive SERS substrate. β-CD is both a reductant for silver ions and a host molecule that binds the analytes which leads to strong SERS enhancement. The method has distinct features: (a) The linear response extends from 0.1 to 60 μM for PRH, and from 1.0 to 100 μM for LOS; (b) the respective limits of detection are as low as 15 nM and 0.92 μM; and (c) the specific SERS bands of PRH and LOS are located at 703 and 1298 cm

Indexed as

Antihypertensive Agentsbeta-CyclodextrinsLosartanMetal NanoparticlesParticle SizePrazosinSilverSpectrum Analysis, RamanSurface PropertiesAntihypertensive Agentsbeta-CyclodextrinsbetadexLosartanPrazosinSilverDFT calculationsHealthcare productsLosartan potassiumPrazosin hydrochlorideSurface-enhanced Raman scatteringβ-Cyclodextrin

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.