Evidence map›Paper›PMID 31741020›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

From metabolic connectivity to molecular connectivity: application to dopaminergic pathways.

Antoine Verger, Tatiana Horowitz, Mohammad B Chawki, Alexandre Eusebio, Manon Bordonne, Jean-Philippe Azulay, Nadine Girard, Eric Guedj

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Molecular connectivity studies in neurotransmission: a scoping review.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
  7. Dopamine D1-Receptor Organization Contributes to Functional Brain Architecture.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  8. Similarity between structural and proxy estimates of brain connectivity.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Antoine VergerDepartment of Nuclear Medicine & Nancyclotep Imaging platform, CHRU Nancy, F-54000, Nancy, France.
Tatiana HorowitzDepartment of Nuclear Medicine, CHU Timone, AP-HM, Marseille, France.
Mohammad B ChawkiDepartment of Nuclear Medicine & Nancyclotep Imaging platform, CHRU Nancy, F-54000, Nancy, France.
Alexandre EusebioDepartment of Neurology and Movement Disorders, CHU Timone, AP-HM, Marseille, France.
Manon BordonneDepartment of Nuclear Medicine & Nancyclotep Imaging platform, CHRU Nancy, F-54000, Nancy, France.
Jean-Philippe AzulayDepartment of Neurology and Movement Disorders, CHU Timone, AP-HM, Marseille, France.
Nadine GirardDepartment of Neuroradiology, CHU Timone, AP-HM, Marseille, France.
Eric GuedjDepartment of Nuclear Medicine, CHU Timone, AP-HM, Marseille, France. eric.guedj@ap-hm.fr.ORCID 0000-0003-1912-6132
Centre National de la Recherche Scientifique · FRCentre de Médecine Préventive · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aims to reveal the feasibility and potential of molecular connectivity based on neurotransmission in comparison with the metabolic connectivity with an application to dopaminergic pathways. For this purpose, we propose to compare the neurotransmission connectivity findings using

methods

resultsThe three dopaminergic pathways (i.e., nigrostriatal, mesolimbic, and mesocortical) were identified by

conclusionThe present study illustrates the feasibility and interest in using molecular connectivity with

Indexed as

Dopamine Plasma Membrane Transport ProteinsParkinson DiseaseDopamineHumansPositron-Emission TomographyRadiopharmaceuticalsTomography, Emission-Computed, Single-PhotonDopamineDopamine Plasma Membrane Transport ProteinsRadiopharmaceuticalsConnectivityDopaminergic pathwaysMetabolismMolecular imagingNeurotransmissionPETSPECT

Identifiers

PMID31741020
OpenAlexW2986629109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.