ArticleScientific reports2019
Different lasers reveal different skin microcirculatory flowmotion - data from the wavelet transform analysis of human hindlimb perfusion.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 42 citations in OpenAlex.
- Acute effects of cold, heat and contrast pressure therapy on forearm muscles regeneration in combat sports athletes: a randomized clinical trial.Scientific reports · 2024Trial
- Acute Effects of the Dry Needling Session on Gastrocnemius Muscle Biomechanical Properties, and Perfusion with Latent Trigger Points - A Single-Blind Randomized Controlled Trial in Mixed Martial Arts Athletes.Journal of sports science & medicine · 2024Trial
- Reactive Hyperemia Reveals Fractal Scaling and Multiscale Complexity in Photoplethysmography Waveforms.Biology · 2026Article
- Exploring Sexual Dimorphism and Genetic Variability in Cutaneous Microhemodynamics in BALB/c, C57BL/6J, and KM Mice.Journal of vascular research · 2026Article
- Homeostatic Responses to Subsystolic Arterial Occlusive Pressure in Glabrous and Non-Glabrous Skin Circulation.Biomedicines · 2026Article
- Optimizing In Vivo Perfusion Assessment by Laser Doppler Flowmetry-Effects of Probe Geometry and Signal Normalization.Diagnostics (Basel, Switzerland) · 2026Article
- Wavelet Components of Photoplethysmography During Reactive Hyperemia: Absolute vs. Relative Metrics.Biology · 2025Article
- Comparing Multiple Versus Sustained Insertion Dry Needling Therapy for Myofascial Neck Pain: A Randomized Controlled Trial.Annals of rehabilitation medicine · 2025Article
- Immediate Effect of Compression Contrast Therapy on Quadriceps Femoris Muscles' Regeneration in MMA Fighters.Journal of clinical medicine · 2024Article
- Regular Physical Activity Seems to Eliminate Lower Limb Perfusion Asymmetries in Sedentary Non-Healthy Older Individuals.Life (Basel, Switzerland) · 2024Article
- Revisiting the Venoarteriolar Reflex-Further Insights from Upper Limb Dependency in Healthy Subjects.Biology · 2024Article
- Benchmarking of Sensor Configurations and Measurement Sites for Out-of-the-Lab Photoplethysmography.Sensors (Basel, Switzerland) · 2023Article
- Studying Erythromelalgia Using Doppler Flowmetry Perfusion Signals and Wavelet Analysis-An Exploratory Study.Biomedicines · 2023Article
- Preclinical study of diabetic foot ulcers: From pathogenesis to vivo/vitro models and clinical therapeutic transformation.International wound journal · 2023Review
- Laterality of blood perfusion in the lower extremities after drinking saline at different temperatures.Scientific reports · 2023Article
- Feasibility of Electrodermal Activity and Photoplethysmography Data Acquisition at the Foot Using a Sock Form Factor.Sensors (Basel, Switzerland) · 2023Article
- Contactless photoplethysmography for assessment of small fiber neuropathy.Frontiers in physiology · 2023Article
- The acute adaptation of skin microcirculatory perfusionFrontiers in physiology · 2023Article
- Diagnostic Features and Potential Applications of PPG Signal in Healthcare: A Systematic Review.Healthcare (Basel, Switzerland) · 2022Review
- Vascular Assessment in Patients With a Lower Limb Wound: A Correlational Study of Photoplethysmography and Laser Doppler Flowmetry Toe Pressure Techniques.Journal of diabetes science and technology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laser Doppler flowmetry (LDF) and reflection photoplethysmography (PPG) are standard technologies to access microcirculatory function in vivo. However, different light frequencies mean different interaction with tissues, such that LDF and PPG flowmotion curves might have distinct meanings, particularly during adaptative (homeostatic) processes. Therefore, we analyzed LDF and PPG perfusion signals obtained in response to opposite challenges. Young healthy volunteers, both sexes, were assigned to Group 1 (n = 29), submitted to a normalized Swedish massage procedure in one lower limb, increasing perfusion, or Group 2 (n = 14), submitted to a hyperoxia challenge test, decreasing perfusion. LDF (Periflux 5000) and PPG (PLUX-Biosignals) green light sensors applied distally on both lower limbs recorded perfusion changes for each experimental protocol. Both techniques detected the perfusion increase with massage, and the perfusion decrease with hyperoxia, in both limbs. Further analysis with the wavelet transform (WT) revealed better depth-related discriminative ability for PPG (more superficial, less blood sampling) compared with LDF in both challenges. Spectral amplitude profiles consistently demonstrated better sensitivity for LDF, especially regarding the lowest frequency components. Strong correlations between components were not found. Therefore, LDF and PPG flowmotion curves are not equivalent, a relevant finding to better study microcirculatory physiology.
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